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Poll: 3- Which of the following tests is most appropriate for confirming hepatitis C in a patient with ele

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Thread: HCV q3

  1. #1
    Anonymous is offline Unregistered Guest
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    HCV q3

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    3- Which of the following tests is most appropriate
    for confirming hepatitis C in a patient with elevated
    ALT and risk factors for the disease?

    A) Aspartate transaminase (AST)
    B) Enzyme immunosorbent assay (EIA-2)
    C) Recombinant immunoblot assay (RIBA-2)
    D) Liver biopsy
    E) Hepatitis C RNA by polymerase chain reaction
    (PCR)

  2. #2
    Anonymous is offline Unregistered Guest
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    answer

    Ans(B) Enzyme immunosorbent assay (EIA-2). AST is a
    nonspecific indicator of hepatopathology and is
    found in many other disease states. Hepatitis C RNA
    noted on PCR is a very specific finding; however,
    this test is expensive. Therefore, PCR should be
    used to monitor the efficacy of therapy, but should
    not be used for screening. Liver biopsy is not diagnostic
    but is useful for determining the stage of liver
    disease and comorbid hepatopathology. RIBA-2 is
    more expensive than EIA-2 and should not be used
    for routine screening.

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