A 26-year-old white male is bitten on the hand by a dog. The patient is allergic to penicillin.

Which one of the following would be the drug of choice for antibiotic prophylaxis in this patient?

Doxycycline (Vibramycin)
Amoxicillin/clavulanate (Augmentin)
Cephalexin (Keflex)
Clindamycin (Cleocin)

Answer --->

Treatment with prophylactic antibiotics for three to seven days is
appropriate for dog bite wounds, unless the risk of infection is low or
the wound is superficial.If frank cellulitis is evident, a 10- to
14-day course of treatment is more appropriate.Amoxicillin-clavulanate
potassium (Augmentin) is the antibiotic of choice for a dog bite. For
patients who are allergic to penicillin, doxycycline (Vibramycin) is an
acceptable alternative, except for children younger than eight years
and pregnant women. Erythromycin can also be used, but the risk of
treatment failure is greater because of antimicrobial resistance.Other
acceptable combinations include clindamycin (Cleocin) and a
fluoroquinolone in adults or clindamycin and
trimethoprim-sulfamethoxazole (Bactrim, Septra) in children. When
compliance is a concern, daily intramuscular injections of ceftriaxone
(Rocephin) are appropriate.

Occasionally, outpatient treatment of infection fails and the patient
needs to be hospitalized and treated intravenously with antibiotics.
Reasons for hospitalization include systemic signs of infection; fever
or chills; severe or rapidly spreading cellulitis or advancement of
cellulitis past one joint; and involvement of a bone, joint, tendon or