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Thread: What are these?

  1. #1
    moveon is offline Junior Member
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    What are these?

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    a. allelic polymorphism
    b. allelic heterogenity
    c. locus heterogenity
    d. heteroplasmy

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    mjl1717 is offline Member
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    Genetics

    Allele -An alternative form of a gene at a particular locus.
    Locus -A place on a chromosome where a particular gene is found.
    Polymorphism-The presence in a population of 2 or more relatively
    common alleles of a particular gene(or forms of a
    chromosome)-the more the alleles the greater the
    polymorphism.
    Genetic Heteogeneity-the term used to describe multiple genetic causes
    of the same or nearly the same phenotype.An example is
    Hemophilia A and Hemophilia B,same phenotype different
    defects.
    Heteroplasmy-???
    Hope this helps.

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    Anonymous is offline Unregistered Guest
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    heterosplamy

    heterosplasmy =variable expressio of mitochondral-transmitted disease
    due to the number of mitochondria bearing the defective mutations.

  4. #4
    moveon is offline Junior Member
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    Genetics

    You both are right. These similar terms confused me.

    Locus heterogenity is seen when a genetic disease caused by mutations at different locus. The clinical picture can be the similar or different. Like OI can be from either chromosone 17 or 7, and APKS from either chromosone 16 or 4.

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