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  1. #1
    IMG SURVIVOR's Avatar
    IMG SURVIVOR is offline Moderator 536 points
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    Need help with this Lung CA Q

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    I know that goljan says that mestastasis is the #1 cause of lung cancer but about primary lung cancer, Goljan says that adenocarcinoma of the lungs is the most common cancer of the lungs because of smoking, and is because of the filters that they put now the bad stuff goes peripherical, and the 2 most common cause is the squamous cell ca Been the 1 in the past.

    now qbank says that squamous is #1 and that adenocarcinoma is not asociated to smoking????

    Help your opinion guys on this one

    thanks
    ps if you want to add anything more better the review
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    why even bother with the obvious. Just know where you are need it and where you can help the most.

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    md90's Avatar
    md90 is offline Senior Member
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    Goljan's Rapid Review Text (pp198-99):

    Primary carcinomas of the lung can be divided into:
    1. non-small cell carcinoma (75%)
    2. small cell carcinoma (20%)

    non-small cell carcinoma (adenocarcinoma) is more responsive to surgery, and more common in women, and is associated with cigarette smoking (but is NOT strong); develops in scars or spread along alveolar walls and mimic lobar pneumonia (bronchioalveoloar), being more peripheral in location

    squamous cell and small cell (oat cell) carcinoma is more centrally located, and both are more common in men and has a strong association with smoking;

    squamous cell CA--tend to cavitate and may ectopically secrete PTH-related protein whereas small cell CA--arise from neuroendocrine cells (Kulchitsky cells), growth is rapid and metastasizes early, and may ectopically secrete ADH or ACTH;

    Also lung cancer among men is decreasing BUT increasing in women...

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