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  1. #1
    Asclepius1's Avatar
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    Which one of the following is the best index of afterload?

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    Which one of the following is the best index of afterload?

    A. Left ventricular end-diastolic pressure
    B. Left ventricular mean systolic pressure
    C. Pulmonary capillary wedge pressure
    D. Total peripheral resistance
    E. Mean arterial blood pressure

  2. #2
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    may be the answer is A

  3. #3
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    My answer is B. Left ventricular mean systolic pressure

  4. #4
    ssrpk is offline Newbie
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    two indices for afterload...

    1)mean arterial pressure
    2)left ventricular peak ventricular pressure
    life is guud

  5. #5
    Asclepius1's Avatar
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    of course it's D

  6. #6
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    Mean arterial pressure (MAP) is better characteristic of afterload change.
    Administration direct positive inotropic agent (dobutamine) increases cardiac output which decrese Total peripheral resistance :

    TPR=(MAP-LAP)/CO
    where MAP- mean Arterial Pressure LAP- left atrial pressure and CO is a cardiac output

    Administration of direct negative inotropic (or chronotropic) agent - propranolol will decrese CO so if MAP didn't changed TPR will increased.

    SO TPR is just the reflexion of changes in CO and MAP.

  7. #7
    Zoe MD is offline Newbie
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    In the Pressure- Volume loop afterload is exactly where the aorta closes which is said to be best index for afterload. And afetrload= diastolic arterial pressure; proportional to peripheral resistance.


    So I think that the answer is B

  8. #8
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    its d

  9. #9
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    Afterload is the presure that the ventricle has to work against to push blood out. So as TPR increases *(higher pressures in the arterial system)so does the afterload, b/c the ventricle has to come up with higher with higher force of contaction in oder to eject the same amount of blood. (keep SV the same) If TPR decreases then aferload decreases. Correct me if i am wrong.

  10. #10
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    Excellent, I agree with you completely

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