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    Roxanita is offline Senior Member
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    Respiratory q4 N*

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    Fetal and maternal erythrocytes have the same concentration of 2,3-bisphosphoglycerate. However, compared with maternal hemoglobin (HbA), fetal hemoglobin (HbF) has a higher oxygen affinity, which facilitates transplacental diffusion of oxygen. The presence of which of the following polypeptide chains in HbF accounts for this finding?

    A) α Chains alone
    B) β Chains alone
    C) γ Chains
    D) Both α and β chains

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    Asclepius1 is offline Ultimate Member 537 points
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    Re: Respiratory q4 N*

    Quote Originally Posted by Roxanita
    Fetal and maternal erythrocytes have the same concentration of 2,3-bisphosphoglycerate. However, compared with maternal hemoglobin (HbA), fetal hemoglobin (HbF) has a higher oxygen affinity, which facilitates transplacental diffusion of oxygen. The presence of which of the following polypeptide chains in HbF accounts for this finding?

    A) α Chains alone
    B) β Chains alone
    C) γ Chains
    D) Both α and β chains
    My guess is C, the gamma chain that cause the increase affinity and causing the oxygen dissociation curve to shift to the left.

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