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Thread: Endocrine q2 N*

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    Roxanita is offline Senior Member
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    Endocrine q2 N*

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    Which of the following tests best distinguishes central diabetes insipidus from nephrogenic diabetes insipidus?
    A) Injection of ADH (vasopressin)
    B) Injection of hypertonic saline
    C) Injection of insulin
    D) Water deprivation
    E) Water loading

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    Asclepius1 is offline Ultimate Member 537 points
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    Re: Endocrine q2 N*

    Quote Originally Posted by Roxanita
    Which of the following tests best distinguishes central diabetes insipidus from nephrogenic diabetes insipidus?
    A) Injection of ADH (vasopressin)
    B) Injection of hypertonic saline
    C) Injection of insulin
    D) Water deprivation
    E) Water loading
    My guess is A. Central diabetes insipidus can't produce ADH so when you inject ADH the kidneys will return to its normal function. Injection of ADH wouldn't do a cat to the dysfuctioned kidneys in nephrogenic DI.

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    kevin ng is offline Newbie 510 points
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    neph diabetic insipidus is due to the receptor defect in the kidney to receive adh, adh may be normal but can't act on the receptor so, my answer is A.

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    ORD
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    Isn't water deprv. would be a better one? E?

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    1- The hormone is produce but when it goes to work, CANT work
    2- There is no creation of hormone, so when you need the hormone, NO HORMONE.

    Now lets put our patient to be water deprive.
    He will need ADH, but you will not be able to diferentiate 1 from 2 .

    But if you gives ADH and he gets better Primary or lack of ADH

    If he does not get better or like goljan says does not raise more than 10% in osmolarity then its secondary.

    So I will go with A
    Moderator: USMLE AND Residency Forums.

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    why even bother with the obvious. Just know where you are need it and where you can help the most.

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