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Thread: Fluids q1 N*

  1. #1
    Roxanita is offline Senior Member
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    Fluids q1 N*

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    A 20-year-old man ingests 1 L of water over 1 hour. Which of the following sets of changes is most likely at the end of the hour?
    ADH / Urine osmolality / Urine flow
    A) ↑ ↑ ↑
    B) ↑ ↑ ↓
    C) ↑ ↓ ↓
    D) ↑ ↓ ↑
    E) ↓ ↓ ↑
    F) ↓ ↑ ↑
    G) ↓ ↑ ↓
    H) ↓ ↑ ↓

  2. #2
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    Asclepius1 is offline Ultimate Member 537 points
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    Re: Fluids q1 N*

    Quote Originally Posted by Roxanita
    A 20-year-old man ingests 1 L of water over 1 hour. Which of the following sets of changes is most likely at the end of the hour?
    ADH / Urine osmolality / Urine flow
    A) ↑ ↑ ↑
    B) ↑ ↑ ↓
    C) ↑ ↓ ↓
    D) ↑ ↓ ↑
    E) ↓ ↓ ↑
    F) ↓ ↑ ↑
    G) ↓ ↑ ↓
    H) ↓ ↑ ↓
    My guess is that volume will suppress ADH release and cause people to pee more and cause the urine to be diluted. so E is my final answer.

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    Roxanita is offline Senior Member
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    uhm...

    I would pick the same...
    ADH / Urine osmolality / Urine flow
    E)↓ ↓ ↑

    ADH (vasopressin), octapeptid hormone 8aa. The stimuli for ADH secretion: * BP decreased / Blood volume decreased or Solute Increased.
    Through: - Baroreceptors: in the Heart (LA) and Blood Vessels (aortic arch and carotid sinus) - Osmoreceptors in the Hypothalamus

    ADH attaches to membrane bound receptors which activates G-protein which increases Cyclic-AMP activity which leads to an increase in the number of water channels in the DCT and CD (by promoting the insertion of Aquaporins-2 protein molecules in the apical membranes of cells lining the DCT and CD.


    Back to the question....

    In this case there is no stimuli for its secretion so...
    *** ADH will be absent:
    *** Low H2O permeability at DCT and CD, little H2O reabsorbed --> Large volume of urine (dilute) -> Urine Flow increased
    *** Hypoosmotic Urine (hypotonic) -> Osmolality decreased


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