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  1. #1
    hunteradam07 is offline Permanently Banned 511 points
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    UW concepts on hypovolemia!

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    Heh folks, i saw these two questions on UW which have the similiar concepts yet two different answers. I would like your opinions on these. The basic concepts are concerned about dehydration (severe) and bleeding. In case of severe dehydration, the answer involved Renal Plama Flow (RPF)=decrease; GFR=increase (RAAS); FF=increase. This i completely agree with since basic physio. Now for bleeding (hypovol shock), the answer are RPF=decrease; GFR=increase; FF=decrease. Their explaination here is compensation is never completed, which is why FF decrease. This is where i m having problem, if we use the same logic of RAAS, then efferent arteriole constriction would increase GFR in this case and an increase GFR has to equal increase in FF, or do they take in account of decrease OCPP due to protein lost from bleeding. Maybe im missing something. What do Yalls think?

  2. #2
    y2kbeegees is offline Newbie 510 points
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    mmm
    probably in bleeding conditions sepcially hypovolemic shock ..initially there is no compensation by kidney but later on total renal shut down occurs ..and so renal plasma flow decreses..GFR SHOULD DECREASE TOO..OVER HERE.. and therefore FF will decrese..

    i think there would be little confusion regarding GFR then over here..
    check it out buddy
    n let me knw
    bg

  3. #3
    y2kbeegees is offline Newbie 510 points
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    hey

    hi hunteradam

    i think i have got lil clear idea about renal plasma flow and ff .. in hypovolemia renal plasma flow decreases and ff is mainly change due to change in renal plasma flow. so here if renal plasma flow is low...plasma spends more time and thus ff is increases.

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