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  1. #1
    IMG SURVIVOR's Avatar
    IMG SURVIVOR is offline Moderator 536 points
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    #15 This Is A Most If You Are Taking The Usmle

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    FILTRATION and CXA




    What will happen to the GFR and to the RPF if you have:

    1-Constriction of the afferent arteriole
    2-Constriction of the efferent arteriole
    3-Increase plama protein?









    1- your GFR will go down your RFP will go down
    2-your GFR will go up your RFP will go down
    3-yor GFR will go down your RFP will not change




    PLEASE GIVE EXAMPLES OF CAUSES THAT CAN GIVE YOU 1,2 OR3

    THANK YOU
    Moderator: USMLE AND Residency Forums.

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    why even bother with the obvious. Just know where you are need it and where you can help the most.

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    md90's Avatar
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    examples...

    decrease in GFR: renal failure, increased age, hypoperfusion of the kidneys

    increase in GFR: diabetics, can be an early sign of diabetic nephropathy; also seen in normal pregnancy

    How can you tell that the GFR is increased or decreased?
    Creatinine Clearance.. is not reabsorbed or excreted BUT filtered in the kidneys






    please correct or add to the information...

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    jguru2 is offline Member 510 points
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    Gfr

    Inulin clearance is used for GFR measurement..it is filtered, but neither secreted nor re-absorbed...
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    St. Matthew's University School of Medicine
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    md90's Avatar
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    creatinine or inulin clearance?

    Inulin clearance is used for GFR measurement..it is filtered, but neither secreted nor re-absorbed...
    Creatinine Clearance.. is not reabsorbed or excreted BUT filtered in the kidneys
    I had to look this up on the internet.. We are both right.

    Glomerular filtration rate (GFR) can be calculated by measuring any chemical that has a steady level in the blood, and is freely filtered but neither reabsorbed nor secreted by the kidneys.
    Creatinine fulfills these requirements to an extent; is a metabolite of creatine found in our muscles; also overestimates the GFR by 10-20% but this is acceptable because of the way it is measured; There are other methods that is more accurate.

    Inulin clearance is one of them but it needs to be infused to maintain a steady state in the blood; Creatinine is already has that steady state therefore it is less work and probably cheap; Remember, on boards, being cheap is the name of the game;


    please post any other information r/t the topic.. we are here to learn.. thank you.

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