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  1. #1
    pharmacology is offline Member
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    suicide by ingesting 25 tablets of extra strength tylenol

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    A 25-year-old woman is despondent that her husband left her for another woman. She attempts suicide by ingesting 25 tablets of extra strength acetaminophen. Her mother finds her and the empty bottle a couple of hours later and immediately rushes her to the emergency room. Which of the following drugs will most likely be given to this patient?

    A. Acetylcysteine
    B. Atropine
    C. Penicillamine
    D. Pralidoxime
    E. Protamine

  2. #2
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    Asclepius1 is offline Ultimate Member 537 points
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    My final answer is A. Acetylcysteine for sure.

  3. #3
    pharmacology is offline Member
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    Re: suicide by ingesting 25 tablets of extra strength tyleno

    Quote Originally Posted by pharmacology
    A 25-year-old woman is despondent that her husband left her for another woman. She attempts suicide by ingesting 25 tablets of extra strength acetaminophen. Her mother finds her and the empty bottle a couple of hours later and immediately rushes her to the emergency room. Which of the following drugs will most likely be given to this patient?

    A. Acetylcysteine
    B. Atropine
    C. Penicillamine
    D. Pralidoxime
    E. Protamine
    Good job.

    The correct answer is A.

    Acetylcysteine (N-acetylcysteine) is the antidote for acetaminophen overdose. It likely acts by replenishing hepatic stores of glutathione, which become depleted in the effort to metabolize the acetaminophen. It is most effective if administered within 10 hours of acetaminophen ingestion.

    Atropine (choice B) is a muscarinic receptor antagonist used in the treatment of cholinesterase inhibitor poisoning.

    Penicillamine (choice C) is a chelating agent used to treat poisoning with copper, lead, arsenic, and gold.

    Pralidoxime (choice D) is an acetylcholinesterase reactivating agent that is used in organophosphorus cholinesterase inhibitor poisoning.

    Protamine (choice E) is used for heparin overdose. Protamine is a basic peptide that binds heparin to form a stable complex devoid of anticoagulant activity.

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