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  1. #1
    Unregistered101 Guest

    One of those questions

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    A pt presents with multiple leiomyomas that are causing chronic pelvic pain. She decides to undergo a total hysterectomy. The histology of the overies demonstrate multiple primary follicles each containing an oocyte. These oocytes are arrested at which of the following stages of cell division?

    a) prophase

    b)metaphase

    c)anaphase

    d)telophase

    e)interphase



    Follow up question: can you please explain if this question has anything to do with the concept of why maternal age has a stronger impact on the risk of trisomies than does paternal age.

  2. #2
    st_55 is offline Member 510 points
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    wouldnt it be in metaphase? from what i understand the oocytes are arrested in prophase of meiosis 1 until ovulation then are arrested in metaphase in meiosis 2 until it is fertilized by sperm...i got this from first aid i hope it helps. i dont think that the maternal age has to to do with this questions...anyone else wanna give it a shot?

  3. #3
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    Isabella21 is offline Junior Member 510 points
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    from Kaplan

    All primary oocytes are formed by month 5 of fetal life and remain arrested in PROPHASE (diplotene) of MEIOSIS 1 until puberty. No oogonia are present at birth. When a girl reaches puberty, a primary oocyte completes meiosis 1 to form a secondary oocyte and polar body. The secondary oocyte becomes arrested in METAPHASE of MEIOSIS 2 and is ovulated. At fertilization within the uterine tube, the secondary oocyte completes meiosis 2 to form a mature oocyte and polar body.

    I hope this help you.......

  4. #4
    lovetiesto is offline Newbie 510 points
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    A) Prophase (46,4n)
    The cell are arrested until puberty. Reason, for increase age and trisomy assocaition is more to do the probablity of Non-disjunction increases w/ increase in age resulting in trisomy.

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