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  1. #1
    Unregistered101 Guest

    Prerenal Failure vs Acute Tubular necrosis

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    How to differentiate between Prerenal failure and Acute tubular necrosis:

    1- ADH is usually high in prerenal failure which leads to water, urea and sodium resorption . The fractional sodium excretion is less than 1% which in acute tubular necrosis is >2%.

    2- Serum urea nitrogen/serum creatinine: Higher ratios (>20) are seen in prerenal azotemia while lower ratios (10-15) are seen in acute tubular necrosis. Normal levels are between 12-20.

    3- Urinary sodium: In prerenal failure is less than 20 while in acute tubular necrosis is greater than 40.

    4- Urine osmolality: >500 in prerenal failure and <350 in acute tubular necrosis.

    5- Urine/serum creatinine: >40 in prerenal failure and <20 in acute tubular necrosis.

  2. #2
    OlyaPushina is offline Newbie 510 points
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