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Thread: hypercalcemia

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    usmlestudy is offline Junior Member
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    hypercalcemia

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    A 59-year-old woman with a 60 pack-year smoking history was diagnosed with lung cancer 2 months ago. She now enters the hospital in coma. Her serum calcium is 16 mg/dL. Which of the following would be the most useful to reduce calcium in this patient rapidly ?

    A. Spironolactone

    B. Hydrochorothiazide

    C. Furosemide

    D. Mannitol

    E. Acetazolamide

  2. #2
    usmlestudy is offline Junior Member
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    Re: hypercalcemia

    Quote Originally Posted by usmlestudy
    A 59-year-old woman with a 60 pack-year smoking history was diagnosed with lung cancer 2 months ago. She now enters the hospital in coma. Her serum calcium is 16 mg/dL. Which of the following would be the most useful to reduce calcium in this patient rapidly ?

    A. Spironolactone

    B. Hydrochorothiazide

    C. Furosemide

    D. Mannitol

    E. Acetazolamide
    (C) CORRECT. Furosemide is the prototype loop diuretic. It inhibit the cotransporter of sodium, potassium , and chloride in the loop of Henle. Inhibition of the transport also results in loss of the lumen-positive potential, which reduces reabsorption of divalent cations as well. As a result, calcium excretion is significantly increased.

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    vphil is offline Newbie
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    Furosemide-

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