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  1. #1
    hunteradam07 is offline Permanently Banned 511 points
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    Can anyone explain the concept of Serum albunin vs. Perioneal albunin gap!

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    Patients with ab ascites, you do a paracentesis. After that you want to measure the alb gap, this will help you to differentiate btw Hepatic causes of ascites or CHF. What i dont understand is how the increase in alb would tell u this? Thanks for yall reply in advance.

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    afzalfilz is offline Newbie 510 points
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    albumin gap actually tells u the difference bw causes of ascites due to portal hypertension like CHF and cirrhosis and causes of ascites without portal hypertension like tuberculosis peritontis ,nephritic syndrom etc
    this is bcoz portal hypertension cause lot of fluid to leak out from circulation devoid of proteins(albumin) that increases the difference bw conc of albumin in circulaton and ascitic fluid so increase the albumin gap
    whereas in causes without portal hypertension there is no difference in albumin conc so gap is less

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    hunteradam07 is offline Permanently Banned 511 points
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    Thanks for the answer. Bottomline if there is no increase in serum alb gap then it rules out ascites as causes right?

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    DR.FNMED's Avatar
    DR.FNMED is offline Junior Member 510 points
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    exactly dear.if there is rise in gap it means the reason is ascites related cases and if there is no increase in gap the causes r others like infection or else.

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    soweto is offline Junior Member 510 points
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    Quote Originally Posted by DR.FNMED View Post
    exactly dear.if there is rise in gap it means the reason is ascites related cases and if there is no increase in gap the causes r others like infection or else.

    ...No, you didnt get it.....
    What is Ascite= Fluid accumulation in the peritoneal cavity.
    What are the causes? Liver/portal HTN?, or others (GI/peritoneal tumors? Pelvic tumors? Granulomatous Infections?)
    How to differentiate between Liver and other causes?
    Calcualte SAAG (Serum Ascites Albumin Gap)
    1- If SAAG >1.1, then the cause is Liver/Portal HTN related
    2- If SAAG<1.1, then the cause lies somewhere else in the others: GI/peritoneal tumors, Pelvic tumors, Granulomatous Infections

    Hope this helps....
    Good luck!
    Soweto from the Ghetto

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