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  1. #1
    shisha's Avatar
    shisha is offline Junior Member 510 points
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    biochem questions can be like this

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    Q 1.

    A patient with anemia shows signs of peripheral neuropathy. His urine malonic acid levels are raised. This has occured due to deficiency of :

    1.]Folic acid
    2.]propionyl coA carboxylase
    3.]Vit B12
    4.]Iron

    Q2.

    A boy comes with muscle weakness upon exercise specially when he is fasting. Also there is rhaddomyolysis and myoglobinuria. It can be due to deficiency of:

    1.]Thiokinase
    2.]CAT( carnitine acyl transferase)
    3.]Fatty acyl CoA synthetase
    4.]Fatty acyl CoA dehydrogenase

    Q3.

    A patient had vomiting ,fasting hypoglycemia and low ketones. He had history of fever for last few days. He went to coma. What other laboratory finding is accompanied with this situation which strongly points towards the diagnosis

    1.]Hyponatremia
    2.]Dicarboxylic acidemia
    3.]Hyperlipidemia
    4.]Hypocalcemia

  2. #2
    shisha's Avatar
    shisha is offline Junior Member 510 points
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    ans1

    vit B12 deficiency[clues were...anemia+peripheral neuropathy+malonic acid in urine]

    ans 2

    CAT deficiency[clues: muscle weakness+rhabdomyolysis+myoglobinuria]

    ans 3

    dicarboxylic acidemia[clues:fasting hypoglycemia+low ketones]

  3. #3
    IMG SURVIVOR's Avatar
    IMG SURVIVOR is offline Moderator 536 points
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    They can also ask about a child that has he tendecy of having alot of fractures and his sclera is blue
    WHat is the way of heritance?
    or
    what is the Dx?

    Or they can ask about a child that has red cherry in the eye what is the DX or what enzyme is deficient?
    Yes I know there are two than could have that.

    In the real exam you can see some easy questions, that you will not beleive they are actually asking you that.
    Moderator: USMLE AND Residency Forums.

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    why even bother with the obvious. Just know where you are need it and where you can help the most.

  4. #4
    stateofequilibrium's Avatar
    stateofequilibrium is offline Super Moderator 6105 points
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    Quote Originally Posted by IMG SURVIVOR View Post

    Or they can ask about a child that has red cherry in the eye what is the DX or what enzyme is deficient?
    Yes I know there are two than could have that.

    In the real exam you can see some easy questions, that you will not beleive they are actually asking you that.
    Yeah, those are the hardest types. You can't believe those questions are what they seem so you spend an inordinate amount of time looking for "tricks" hahahaha
    Posterior Fornix.

  5. #5
    ray farrell is offline Member
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    Where did you get the Qs from! Just curious.

  6. #6
    IMG SURVIVOR's Avatar
    IMG SURVIVOR is offline Moderator 536 points
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    Quote Originally Posted by ray farrell View Post
    Where did you get the Qs from! Just curious.
    My questions I just made them up.

    Yes I know Im the best .

    After you have prepare for the USMLE STEP1, you can make questions from top of your head, besides Im the mod, Im expose to USMLE step1 material all the time, so Im not a genius, anybody with half of a brain can do it,after good preparation and exposure to the material
    Moderator: USMLE AND Residency Forums.

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    why even bother with the obvious. Just know where you are need it and where you can help the most.

  7. #7
    IMG SURVIVOR's Avatar
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    Quote Originally Posted by stateofequilibrium View Post
    Yeah, those are the hardest types. You can't believe those questions are what they seem so you spend an inordinate amount of time looking for "tricks" hahahaha
    And people waste time looking for the trick, because you dont beleive that USMLE will ask something so easy, and they mark the wrong answer
    Moderator: USMLE AND Residency Forums.

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    why even bother with the obvious. Just know where you are need it and where you can help the most.

  8. #8
    Hatim is offline Junior Member 510 points
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    that easy???? thats like not even USMLEWORLD LEVEL how many of those are there!?!??!

  9. #9
    IMG SURVIVOR's Avatar
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    Quote Originally Posted by IMG SURVIVOR View Post
    They can also ask about a child that has he tendecy of having alot of fractures and his sclera is blue
    WHat is the way of heritance?
    or
    what is the Dx?
    1- AD= Autosomal Dominant
    2- Osteogesis Imperfecta or brittle bone dissease.

    Who can answer the second question?
    Moderator: USMLE AND Residency Forums.

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    why even bother with the obvious. Just know where you are need it and where you can help the most.

  10. #10
    shisha's Avatar
    shisha is offline Junior Member 510 points
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    It is tay sachs disease with cherry red spots in macula which can lead to blindness.it is due to deficiency of hexosaminidase A.

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