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Thread: p53

  1. #1
    IMG SURVIVOR's Avatar
    IMG SURVIVOR is offline Moderator 536 points
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    p53

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    Simple questions
    1- why do we need P53?
    2- What can happend if we dont have P53?
    3-What diseases are related to P 53?
    4- will you have this on your USMLE STEP 1 test?
    5- add anything else will be nice
    Moderator: USMLE AND Residency Forums.

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    why even bother with the obvious. Just know where you are need it and where you can help the most.

  2. #2
    MDiva's Avatar
    MDiva is offline Member 511 points
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    1. p53 is the tumor-suppressor that guards our genome.
    2. Without it, our cells that are defective or mutated complete the cell cycle, instead of being called out by p53, and made to undergo apoptosis.
    3. Li-Fraumeni syndrome, which involves multiple system tumors.
    4. I am most certain it will be there.
    5. I'll add a follow-up question. Which part of the cell cycle does p53 work in?
    I used to pray and pray for a bike and never got one. Later I learned that God doesn't work that way... so I went out and stole a bike and asked God for forgiveness.

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