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  1. #1
    IMG SURVIVOR's Avatar
    IMG SURVIVOR is offline Moderator 536 points
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    Glycolisis Steps

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    Glycolysis steps
    "Goodness Gracious, Father Franklin Did Go By Picking Pumpkins (to) Prepare Pies":
    Glucose
    Glucose-6-P
    Fructose-6-P
    Fructose-1,6-diP
    Dihydroxyacetone-P
    Glyceraldehyde-P
    1,3-Biphosphoglycerate
    3-Phosphoglycerate
    2-Phosphoglycerate (to)
    Phosphoenolpyruvate [PEP] Pyruvate · 'Did', 'By' and 'Pies' tell you the first part of those three: di-, bi-, and py-.
    · 'PrEPare' tells location of PEP in the process.
    Moderator: USMLE AND Residency Forums.

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    why even bother with the obvious. Just know where you are need it and where you can help the most.

  2. #2
    md90's Avatar
    md90 is offline Senior Member
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    questions r/t the actions of glucose...
    1. In relation to the peripheral uptake of systemic tissues, what tissue(s) gets regulated in the amount of transporters in the transport of glucose?

    2. what does glucose go into tissues as?
    "SLAM-DUNK THE STEPS"

    “Peace, it does not mean to be in a place where there is no noise, no trouble, or no hard work…..it means to be in the midst of those things and still be calm in your
    heart.”

  3. #3
    ZWobble is offline Junior Member 510 points
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    Ok so glucose goes into tissue as glucose 6 phosphate, I'm not sure however whats limited...do you mean the SGLUT1 Na/glucose symporter?

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    md90's Avatar
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    Quote Originally Posted by ZWobble View Post
    Ok so glucose goes into tissue as glucose 6 phosphate, I'm not sure however whats limited...do you mean the SGLUT1 Na/glucose symporter?
    the sugars, not just glucose, all get phosphorylated (fructose and galactose)... so you are right, zwobble;

    in relation to the other question... I am talking about the GLUTs and insulin and their role in the uptake of glucose... the liver has its' own receptors for glucose; Glut2 is for pancreas but usually for stimulation to release insulin and inhibit the alpha cells to release glucagon, NOT necessarily for the uptake; whereas the adipose and muscle tissues need Glut4 and insulin to help in the uptake of glucose; BUT if this question is asked in the exam... choose adipose tissue (BEST) then choose muscle, why? Muscle has anaerobic glycolysis to make glucose...

    Hope that this better explain the question and answer, and I apologize for the confusion...
    "SLAM-DUNK THE STEPS"

    “Peace, it does not mean to be in a place where there is no noise, no trouble, or no hard work…..it means to be in the midst of those things and still be calm in your
    heart.”

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    md90's Avatar
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    I apologize... I just recognized the error in the question... I stated the "actions of glucose" instead of "action of insulin".... As Goljan states: "What an idiot!!" that's me... in a fun way of course...
    "SLAM-DUNK THE STEPS"

    “Peace, it does not mean to be in a place where there is no noise, no trouble, or no hard work…..it means to be in the midst of those things and still be calm in your
    heart.”

  6. #6
    IMG SURVIVOR's Avatar
    IMG SURVIVOR is offline Moderator 536 points
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    BUMP this thread
    Moderator: USMLE AND Residency Forums.

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    why even bother with the obvious. Just know where you are need it and where you can help the most.

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    surewill is offline Newbie 510 points
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    we will all make errors some time some where some how...but its important to start thinking about topics that we may not have thought much about. So thank you for the stimulation!it helps me...

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    k_tanaka is offline Senior Member 511 points
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    Quote Originally Posted by md90 View Post
    the sugars, not just glucose, all get phosphorylated (fructose and galactose)... so you are right, zwobble;

    in relation to the other question... I am talking about the GLUTs and insulin and their role in the uptake of glucose... the liver has its' own receptors for glucose; Glut2 is for pancreas but usually for stimulation to release insulin and inhibit the alpha cells to release glucagon, NOT necessarily for the uptake; whereas the adipose and muscle tissues need Glut4 and insulin to help in the uptake of glucose; BUT if this question is asked in the exam... choose adipose tissue (BEST) then choose muscle, why? Muscle has anaerobic glycolysis to make glucose...

    Hope that this better explain the question and answer, and I apologize for the confusion...
    Exercising muscle does not need insulin for uptake of glucose. Adipose, exercise or not you will need insulin for GLUT 4 uptake of glucose

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