38 year old male in rural area presents to a physician for an employment physical; The ocular exam shows a small opaque rings on the lower edge of iris in anterior chamber of eye; Nodular lesions are found on the Achilles tendon; Therapy will be aimed at increasing which gene products in teh hepatocyte cell membrane?

APO B-100 receptor, why? this is Familial hypercholesterolemia, and it's autosomal dominant; the pathognomonic findings are xanthomas and arais lipoides (what was found on the ocular exam); has a very high LDL b/c of deficient endocytosis of LDL particles by LDL receptors; the treatment is to increase the genetic expression of LDL receptors, dietary changes, resin drug, niacin, or HMG-CoA reductase inhibitor;