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  1. #1
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    IMG SURVIVOR is offline Moderator 536 points
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    #11 MD90 I need your help on this one

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    What mineral those hemoglobin needs to transport properly O2?
























    Iron

    Md90 I remember you did a very good post about Iron and methahemoglobilenemia and the iron absorption. can you please review that for us thank you
    Moderator: USMLE AND Residency Forums.

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    why even bother with the obvious. Just know where you are need it and where you can help the most.

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    methemoglobinemia

    What is it?
    too much methemogloblin(MetHb) in the blood, and iron is Fe+3

    What happens when Fe+3?
    Oxygen can not bind, and it affects the SaO2 by decreasing the sats and the person can be cyanotic
    will also see chocolate colored blood..

    What can cause MetHb?
    1. Drugs (e.g. Sulfa or nitrite drugs), how? are oxidizing agents; and can cause hemolytic anemia in G6PD
    2. deficiency of MetHb reductase--not able to convert Fe+3 to Fe+2

    What is the treatment?
    1. primary treatment: IV methylene blue
    2. ancillary treatment: Vitamin C, why? reducing agent

    In what patients can you see this problem more frequently? HIV patients..
    why? on treatment for pneumocystsis carinii...with the drug TMP-SMX which is an oxidizing agent!!!
    Last edited by md90; 04-26-2006 at 01:36 PM.

  3. #3
    IMG SURVIVOR's Avatar
    IMG SURVIVOR is offline Moderator 536 points
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    Son an oxidizing agent will give you methahemoglobinemia?

    I know that they will give you hemolytic anemia and some patients like g6p deficiency but this is new to me. WAO
    Moderator: USMLE AND Residency Forums.

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    why even bother with the obvious. Just know where you are need it and where you can help the most.

  4. #4
    md90's Avatar
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    straight from Goljan audio lectures and Rapid Review...

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