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  1. #1
    whereistheidnotinuse is offline Junior Member 510 points
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    Acetoacetyl-CoA in the b-oxidation of fatty acids

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    I read in a question I was studying that;
    Acetoacetyl-CoA is involved in the
    b-oxidation of fatty acids

    I don't understand where it comes. Could anybody help???

  2. #2
    hdu
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    Look at the last round

    In each round a two carbon fragment is released as acetyl CoA.
    In the process of betaoxidation a beta-ketoacyl is formed in each round before the compound is broken into acetyl CoA and an acyl CoA with 2 carbon less than the original.
    So, in Beta oxidation of palmityl CoA you have 16 C, after the 1st round you have 14 C and so...
    In the last round you have a Beta-ketoacyl of only 4 carbons. This beta-ketoacyl is acetoacetyl CoA, before being broken into two acetyl CoA.

  3. #3
    mog
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    Oh thank you SO MUCH hdu for your clear explanation. So it was in the last portion of oxidation then. I'd better revise it all over again. Thanks again for your input!

  4. #4
    desai29 is offline Member 512 points
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  5. #5
    Vmchri is offline Newbie 510 points
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    How Acetoacetyl co A produce energy when it enters beta oxidation anyone explain

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