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Asclepius1
11-28-2004, 10:27 PM
Can you try to explain why surgery is not permitted for Crohns patients?

Asclepius1
11-28-2004, 10:29 PM
Can you try to explain why surgery is not permitted for Crohns patients?

Good question. Why?

Asclepius1
11-28-2004, 10:35 PM
Can you try to explain why surgery is not permitted for Crohns patients?

Keep in mind that Crohn's disease can involve any segment of the GI (gastro-intestinal) tract from mouth to anus and can effect all layers of the bowel ie. the mucosal, muscular and outer layer . Ulcerative Colitis effects only the large bowel or colon, and only involves the mucosal or inner layer of the colon.

Briefly, in ulcerative colitis, removing the colon removes the organ that is diseased and therefore removes the disease. It is "the cure" for ulcerative colitis. No more colon, no more disease. In Crohn's disease however, the small bowel (intestine) is frequently involved. Removing the colon in Crohn's disease patients does not eliminate their disease because the disease can flare up in the remaining small intestine. Therefore, this surgery would not be a cure or solution for Crohn's disease patients.

Asclepius1
11-28-2004, 10:41 PM
FDA today licensed a new biotechnology product to treat patients with moderate to severe Crohn's disease, a chronic, incurable inflammatory bowel disease that causes diarrhea, cramping and abdominal pain and in some cases open holes (fistulae) leading from the intestine to the skin.
The new product, a monoclonal antibody called infliximab, is the first approved treatment for Crohn's disease. It is a genetically engineered antibody against a protein, tumor necrosis factor alpha, that promotes inflammation in the body. This antibody is manufactured using cells containing human and mouse antibody genes.

"Although not a cure, in the short-term, infliximab can have a dramatic impact on the quality of life of patients with severe forms of Crohn's disease," said Acting FDA Commissioner Michael A. Friedman, M.D. "We look forward to more long-term studies of the product so that patients and their doctors can use it in the most effective way possible."

Asclepius1
04-26-2005, 06:08 PM
In crohn's disease surgery is indicated only in cases of acute obstruction, resecting only the obstructed segment and not all the affected area because doing so would cause short bowel syndrome

Asclepius1
05-14-2005, 03:27 PM
Can you try to explain why surgery is not permitted for Crohns patients?

Good question. Why?BECAUSE WHEN YOU CUT THE VICERA ANYWAY, THE EPITELIUM STILL PRESENT THE SAME PATOLOGY AND THEN THE ABSORTION IS LOW, AND MORE DIARREA







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