PDA

View Full Version : pharmacology local anesthetics



SONALI SEN
01-01-2007, 07:38 AM
What is the effect of "infection" on the action of local anesthetics

SONALI SEN
01-03-2007, 04:13 AM
since infection will decrease the pH extracellularly.......more local anesthetic [which are usually weak bases] .....will be in the NH3+ form [ionized/protonated].....and so entry into the cell will be decresed.....Meaning by more local anesthetic will be required to cause a state of anesthesia.







Copyright © 2003-2018 ValueMD, LLC. All rights reserved.