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IMG SURVIVOR
04-02-2006, 01:56 PM
1- Mechanism of action of the benzodiazepins?
2-Antidote for Benzodiazepins?










1- Binding of GABA to its receptors on the cell membrane triggers and opening of chloride channel, which leads to and increase in conductance. In conclusion you will have small HYPEPORALIZATION .
2-flumazenil

Scott1981
04-02-2006, 02:19 PM
"frenzo"-diazepins---- opens chloride channels more "FRE"QUENTLY

barbituates- opens chloride longer.

ahhh..... ok...... i cant plagerize...... thats from first aid.... hehehe

IMG SURVIVOR
04-02-2006, 02:23 PM
"frenzo"-diazepins---- opens chloride channels more "FRE"QUENTLY

barbituates- opens chloride longer.

ahhh..... ok...... i cant plagerize...... thats from first aid.... hehehe


It doest not matter you putting in your portion to help

THANKS

Semitallsmalls
12-08-2006, 03:59 PM
the way we learned it in class was that its not the BDZs that are opening the GABAa Cl- channel; its still being opened by GABA binding to GABAa. When BDZs bind to the BDZ receptor it enhances the opening of the Cl- channel so that there is a greater hyperpoloarization. BDZ --> hyperpolarization is therefore an action potential dependent event. In contrast barbiturates directly open the GABAa channel and is therefore an action potential independent event.

what do u guys think about that?

sarda
12-20-2006, 01:58 PM
bzd-----increses frequency of opening cl- channel
barbiturates-----increses duration







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