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  #11 (permalink)  
Old 03-20-2007, 10:54 AM
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MDIVA - my condolences... I'll notify my friends & family.
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  #12 (permalink)  
Old 03-20-2007, 05:28 PM
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My condolences also, sudden events such as these are never easy.

I have tried to look into this a little and the company seems to be blaming the wheat gluten ingredient of their foods for the problem. This would seem to indicate some type of fungal contamination which has been a problem in the past with aflatoxin. One source suggested orchotoxin, if I remember correctly. Symptoms seem to have some resemblance to ethylene glycol (antifreeze) toxicity according to some veterinarian postings on VIN (veterinary information network). The kidney seems to be the target organ or the organ most affected leading to acute renal failure.

Although Hill's products don't seem to be directly affected, they are also voluntarily recalling some of their products (also from VIN).

I will try to keep up on this and post any definitive findings as time permits.
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  #13 (permalink)  
Old 03-21-2007, 11:23 PM
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Thank you all for your condolences, I appreciate it. An update: turns out our cat died not of the food, but of ingestion of rat posion. A neighbor came and saw our cat and noticed the gunk around his mouth, which I took to be the vomitus and said that his cat died the same way a couple years back. He showed us the poision in the alley, sure enough, it looks like pet kibble, but a weird greenish blue color.
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  #14 (permalink)  
Old 03-23-2007, 02:47 PM
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Rat poison in the pet food!

Now on the news there are stories that the pet food recently recalled was tainted with rat poison. So as it is, we were right AND my neighbor was right in speculating how my cat died recently...honestly, who does this kind of f*&^#ed-up pooh pooh?????? WHAT IS WRONG WITH PEOPLE????? I am overwhelmingly disgusted right now.
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  #15 (permalink)  
Old 03-23-2007, 03:05 PM
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sorry to hear
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  #16 (permalink)  
Old 03-23-2007, 04:01 PM
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Quote:
Originally Posted by MDiva View Post
Now on the news there are stories that the pet food recently recalled was tainted with rat poison. So as it is, we were right AND my neighbor was right in speculating how my cat died recently...honestly, who does this kind of f*&^#ed-up pooh pooh?????? WHAT IS WRONG WITH PEOPLE????? I am overwhelmingly disgusted right now.
Yes, it appears as if a type of rat poison is the most likely agent causing problems in the pet food recall. The over-the-counter rat poisons used in the U.S. are not the same as the suspected agent in this case, however. The suspected agent is aminopterin.

The info below is taken from a website for veterinary professionals (VIN) I mentioned earlier: [The wikipedia link above is better for more general info]

Quote:
What is Aminopterin?
Aminopterin (4-aminopteroic acid) is a folic acid inhibitor (analog of folic acid). It was originally used as an antineoplastic agent in the late 1940s, but was superceded by methotrexate, a related, but less toxic folic acid analog.

What is aminopterin used for today?
While it is currently undergoing renewed clinical interest as an antineoplastic, it is predominantly used as a rodenticide in some countries. This use is not legal in the United States.

What toxicity is associated with aminopterin?
The toxic side effects listed below are extrapolated from those reported for methotrexate. We suspect that they apply to aminopterin, but caution readers that this is not certain.
At high doses, methotrexate results in deposition of 7-hydroxymethotrexate in the renal tubules, resulting in crystalluria and acute renal failure.
Methotrexate also inhibits DNA/RNA synthesis by inhibiting folate synthesis (competitive reversible inhibition of dihydrofolate reductase). Folate is required for thymidine synthesis (one of the nucleoside precursors of DNA). This leads to cell death of rapidly-dividing cells (blood cells, GI cells).
From current evidence, it appears that aminopterin toxicity is analogous to methotrexate toxicity.


How is aminopterin toxicity treated?
The nephrotoxicity is treated with aggressive hydration and diuresis to dissolve and remove the crystals from the tubules. Based upon reports in humans and reports by colleagues in this current situation, at least partial renal recovery can be anticipated in many cases.
Bone-marrow suppression (myelosuppression) is a concern with any folic acid inhibiting agent. A small number of VINners have reported anemia in patients exposed to the affected foods.
Thus far there are no reports of thrombocytopenia or leukopenia, but these effects may not be apparent until later in the disease process.
At this point, it is impossible to say if this potential effect needs to be addressed. Certainly changing the food fed and removing the insult is the most important step and may be adequate.
Folinic Acid (NOT FOLIC ACID) can be considered prophylactically to prevent or minimize myelosuppression and mucositis. Antibiotic therapy may be necessary in cases of severe neutropenia. Folinic acid doses are 1mg/kg/day PO.
Gastrointestinal damage may result in endotoxemia, diarrhea and vomiting. Supportive therapy is indicated if these signs are observed in an exposed patient.
There is precedent for companies to reimburse pet owners for medical expenses incurred for these incidents. I would encourage anyone affected by this to look into this possibility.

Again, my sincere apologies to anyone and everyone affected by this unfortunate event.
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  #17 (permalink)  
Old 03-23-2007, 06:45 PM
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Those companies should pay the price, law suit !!!
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Old 03-24-2007, 11:49 AM
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I am so sorry to hear about your cat. I would deff sue them, there is a class action lawsuit in the works. Many dogs/cats have died in the past few weeks bc of this.

I know that it wont bring the kitty back, but at least it will, hopefully, make the company check their quality control twice before shipping out their food.
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  #19 (permalink)  
Old 03-26-2007, 11:13 AM
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Thanks again, everyone. There are a couple of class action law suits in the making.
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Old 03-26-2007, 11:22 AM
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Very sorry to hear that. Sue, seriously.
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