Problem 7: Promoters
Promoters for eukaryotic mRNA synthesis:
A. are more complex than prokaryotic promoters
B. can require binding of multiple transcription factors to form a transcription complex
C. have specific DNA sequences such as the "TATA" box that are recognized by proteins
D. are the stretches of DNA to which RNA polymerase binds to initiate transcription
E. all of these



Eukaryotic Transcription Complex

The structure of a eukaryotic transcription complex contains many more transcription factors than a procaryotic transcrption system. These proteins are needed to recognize the specific DNA sequences in the eukaryotic promoter to which RNA polymerase binds to initiate transcription.
The transcription complex positions RNA polymerase at the beginning of a eukaryotic gene. The complex contains basal factors, such as the TATA-binding proteins. The RNA polymerase requires multiple transcription factors to form the transcription complex that recognizes specific sequences such as the "TATA" box that preceeds the start site for pre-mRNA synthesis.



ans:
E. all of these
In addition to these general features of eukaryotic promoter recognition, there are many transcriptional activitors that bind to DNA elements known as "enhancers" and help promote the initiation of RNA synthesis for specific genes.