HY Concept 190 (IMMUNO IS TOUGH, YOU BETTER DRAW A PIC!)

[tommyk]

ok, BIG POINT:

You have to understand the basics of activation. IF say an antigen presenting cell (Dendrocyte, B-cell, Macrophage) [T-CELL ARE NOT ANTIGEN PRESENTING!!!!], binds an antigen (virus), then CROSSLINKING occurs and the cell gobbles up antigen and then PRESENTS IT ON THE SURFACE. A lot of you know that, but THEN you must follow the storyline. And lovely young helper T cell comes along and attaches or holds hands with the antigen presenting cell. THEN, the T-helper cell "blushes red" and is so happy she throws out IL-2, IL-4, and IL-5 that stimulate both B-cells and T-cells (IL-2 here). Some of the activated B-cells from what kind of cells in the secondary response and what is the most common surface Ig?

[tommyk]

A few activated B-cells turn INTO MEMORY CELLS (BEFORE, THEY WERE PLASMA CELLS), and they usually have IgG on top of them for rapid response to reexposure.

IMMUNO IS REALLY TOUGH SO I HOPE YOU GUYS DON'T GET TOO MANY QUESTIONS, BUT THE GOOD THING IS THAT THE NBME IMMUNO QUESTIONS OFTEN RANGE FROM SUPER BASIC TO SUPER DUPER HARD.
GET THE EASY ONES RIGHT!