A 55-year-old diabetic male has necrotizing fasciitis involving the left upper thigh. Necrotizing fasciitis is characterized by which of the following statements:
A This process tends to remain localized.
B Histologically, foreign body giant cells are numerous.
C It is usually due to viral infection.
D It is typically the result of severe atherosclerosis.
E Penetrating trauma may precede its occurrence.
(E) CORRECT. The trauma introduces the infection into deep soft tissues.
M.D., PGY-3 Internal Medicine