Welcome
scubadoc has joined the chat.
[voodooMD] hello out there
[Unregistered] hello
[sm79] hello>?
[Unregistered] I am the big kaouna
[Unregistered] tonights pharm chat will begin at 11:00pm est
[noon] yousef chat at 11
[Yousef] ok
[Yousef] :gun
[noon]
[Unregistered] hello noon
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Now entering USMLE_Step_1 subroom.
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[anniegeorge] hi hi
[scubadoc] hey everybody
[anniegeorge] we'll start ?
[Unregistered] so what topic r we discussing tonight
[anniegeorge] CNS
[Unregistered] ok
[anniegeorge] Benzodiazepines and Barbiturates both have action on CL- ion channel ? How do they differ ?
[Unregistered] bendiaz increase the frequency
[Unregistered] barbs increase the duration of cl channels
[anniegeorge] BDZ- potentiate GABA by inc the frequency of CL ion channel opening. Barbits inc the duration of Cl- ion channel opening. yeah you are right unregistered
[Victor_E] frequency vs duration
[Unregistered] true
[anniegeorge] Name the drug that would be given to antagonize the action of BDZ ?
[Unregistered] flumazenil
[Victor_E] flumazenil
[anniegeorge] right on man !
[anniegeorge] Flumazenil
[Unregistered] thnaks
[anniegeorge] Out of all the BDZ name the three that do not undergo hepatic metabolism ?
[Victor_E] out the liver
[anniegeorge] Oxazepam , Temazepam , Lorazepam
[anniegeorge] right
[Unregistered] true
[Victor_E] oxazepam, temazepam and lorazepam
[Unregistered] the short acting ones
[anniegeorge] Which group of S-H is contraindicated in Porphyrias and why ?
[Victor_E] barbs
[Unregistered] true
[anniegeorge] this is going to be a fast session tonight ok , I have am not doing well
[anniegeorge] Barbiturates because they increase HEME synthesis
[anniegeorge] Name the BDZ used in Status Epilepticus ?
[Victor_E] not doing well, what do you mean?
[Unregistered] do they act on some specific enzyme in heme synthesis
[Unregistered] diazepam
[Victor_E] diazepam, lorazepam
[anniegeorge] well sick , weak was in bed two days...
[anniegeorge] Lorazepam
[anniegeorge] right
[Unregistered] my first choice would be diazepam
[Victor_E] sorry to hear that annie. we don't need to do this if you're not feeling well
[anniegeorge] no no , Let me finish
[Unregistered] lorazepam more commonly used in women
[Unregistered] ok
[anniegeorge] I will feel bad that I just did not keep my end of the bargain !
[anniegeorge] thanks Vic
[anniegeorge] Name the step in Ethanol metab that is inhibited by Disulfiram ?'
[anniegeorge] why unregistered ?
[anniegeorge] used in women ?
[Unregistered] acetaldehyde dehydrogenase
[Victor_E] how about we compromise and do half an hour instead of one hour?
[anniegeorge] sure
[anniegeorge] Acetaldehyde------------ –Acetealdehyde Dehydrogenase (mitochondria) ---------Acetic Acid
[Unregistered] thats what i he=ad heard in one of the live lectures casette that it is more suitable for women
[Victor_E] aceta dehyro
[anniegeorge] right on guys !
[anniegeorge] What the dangers of consuming Methanol ?
[Unregistered] blindness
[anniegeorge] Formic Acid – Occular damage Severe Anion Gap Metab Acidosis, Resp Failure
[anniegeorge] Name the anticonvulsants that act by facilitating GABA mediated hyperpolarization
[Victor_E] anion gap met acidosis
[Unregistered] diazepam
[anniegeorge] Barbiturates and Benzodiazepines Barbiturates and Benzodiazepines
[Unregistered] ok
[anniegeorge] right ?
[anniegeorge] next is my attempt at making USMLE questions !
[Victor_E] ah, trick question *evil*
[Unregistered] true
[anniegeorge] A pt being treated for epilepsy presents to her physician with complaints of increased hair growth , gingival hyperplasia , and ugly acne all over her face ! On peripheral blood exam she has granulocytopenia and megaloblastic Anemia . What is the likely drug this pt has been taking ?
[anniegeorge]
[Unregistered] phenytoin
[anniegeorge] right on !
[anniegeorge] Phenytoin.
[Victor_E] phenytoiing
[Victor_E] i type too slow
[anniegeorge] thats ok , I will wait
[anniegeorge] What is the DOC for trigeminal neuralgia ?
[Victor_E] no its ok
[Unregistered] i know this give me choices
[anniegeorge] Diazepam , Chloramphenical , Clorpromazine , Carbamazepine
[Victor_E] i dont know this one
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[anniegeorge] CARBAMAZEPINE
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[anniegeorge] What you prescribe in case of ABSENCE seizures ?
[noon] carbam
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[Victor_E] valproic acid, ethosuximide
[ppliutcm] ethosximide
[noon] valp acid
[Unregistered] sorry guys i got logged out
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[Unregistered] so what was the ans for the last qs annie george
[anniegeorge] right on guys
[Victor_E] unregistered, you should log in using a regular account because you will get booted everytime a guest tries to enter the chat
[Unregistered] was it carbamazepine
[anniegeorge] Ethosuximide Valproic Acid and Clonazepam
[anniegeorge] :cl
[Unregistered] for doc of trigeminal neuralgis was it carbamaz
[anniegeorge] What is fetal hydantoin syndrome ?
[anniegeorge] yes yes unreg
[Unregistered] alochol consump in pregnancy
[anniegeorge] no no
[Unregistered] thanks
[noon] valp acid is for all seiz
[anniegeorge] It is the adverse effect of Phenytoin and it includes cleft lip and palate .
[Victor_E] anti convulsants in pregnancy will cause it
[anniegeorge] yes
[anniegeorge] not alcohol
[Unregistered] valproic acid i most commonly used in ones who cannot take clonazepam
[anniegeorge] Name an IV anesthetic used in out patient surgery ?
[Victor_E] phenytoin i think
[Unregistered] i dont think phenytoin causes fetal hydantoiin suynd
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[Unregistered] lidocaine
[anniegeorge] yes yes yes , courtesy Kaplan pharmacology
[anniegeorge] Propofol
[Unregistered] why not lidocaine
[Unregistered] cause lidocaine is used very commonly in opd
[anniegeorge] is Lidocaine given IV for anethetic purpose ?
[Unregistered] yes it is
[anniegeorge] ok then
[noon] save with pregnancy ?
[anniegeorge] What is Malignant Hyperthermia ? What causes it ?
[Unregistered] haloperidol caused it
[Victor_E] isn't lidocaine a local anesthesitic....not iv....right?
[anniegeorge] thats what I thot
[Unregistered] it can be gibven iv also
[anniegeorge] but hey I have to look that up
[anniegeorge] alright Unreg
[Unregistered] it is a class 2 antiarrhythmic i think
[anniegeorge] Succinylcholine, d-tubocurarine
[anniegeorge] yes thats right
[anniegeorge] it is antiarrhythmic
[Unregistered] whats is the treatment for malignant hyperthermia
[anniegeorge] What is the receptor on which Morphine and Methadone and Miperidine act as agonists ?
[Unregistered] mu receptors
[Victor_E] MU
[anniegeorge] yeah right on
[anniegeorge] Mu
[anniegeorge] Why is Levodopa given along with carbidopa ?
[Unregistered] so that it can cross bbb
[Victor_E] helps it cross bbb
[anniegeorge] Carbidopa inhibits peripheral AAAD and increases CNS availability of Ldopa
[Unregistered] tell me the treatment for malignant hyperthermia
[Unregistered] thaaats what i said it helps crosess the blood brain barrier
[anniegeorge] you are right !!!!!
[totumito] dantrolene
[Unregistered] right
[anniegeorge] :box
[Unregistered] how does dantrolene act
[Unregistered] moa of dantrolene
[anniegeorge] looks like somebody is ready to punch me in the face !
[Unregistered] no take tot cool friend
[Unregistered] we all are learning and helping each other
[anniegeorge] it acts n the calcuim channle
[Unregistered] true
[anniegeorge] right on !
[anniegeorge] Name an MAO B inhitor used in treating Parkinsonism ?
[Unregistered] it actis on ca ch in the sarcoplasmic reticulum
[anniegeorge] right
[Unregistered] amitryptyline
[ppliutcm] selegiline
[Victor_E] selegiline
[anniegeorge] SELigiline
[Unregistered] selegilline thats right
[anniegeorge] Name M receptor Blockers used in treating Parkinsonism
[Victor_E] benztropine
[Victor_E] trihexyphenidyl
[Unregistered] name a mao inhiboitor which will not cause the adverse effects with tyramine and cheese
[anniegeorge] Benztropine and Trihexyphenidyl
[anniegeorge] MAO B inhibitors
[Victor_E] agree
[anniegeorge] What side effect of Clozapine warrants a weekly blood test ?
[Victor_E] mao - A (Allover), mao - b (brain)
[Unregistered] agranulocytissis
[anniegeorge] right on unreg !
[Victor_E] agranulo
[anniegeorge] Agranulocytosis
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[anniegeorge] What is Neuroleptic Malignant Syndrome and how do you treat ?
[Unregistered] so whiuch mao will not cause side effects with tyramine and cheese guys
[Victor_E] dantrolene
[Victor_E] and bromocriptine
[Unregistered] dantrolene is the treatment
[anniegeorge] MAO A
[anniegeorge] Bromocriptine and Dantrolene
[Unregistered] which one
[Unregistered] it is moclohemide
[Victor_E] D2 block caused by haloperidol
[anniegeorge] phenelezine
[Unregistered] moclohemide is the one which will not cause side effects with tyramine
[anniegeorge] tranylcypromins
[Unregistered] phenelzine will cause
[Victor_E] good one unreg, i didnt know that
[anniegeorge] yes thats what you asked
[Unregistered] phelezine tranycypromine and isocarboxazid will caus se
[anniegeorge] MOclohemide is it s MAO b inhitior ?
[Unregistered] but when u give moclohemide it will not cause
[Unregistered] it is a mao a inhibitor i think
[anniegeorge] ok
[anniegeorge] V
[Unregistered] so will leave mao b to brealk down the tyramine products annieg
[anniegeorge] What are the three ‘Cs’ that are are side effects of TCAs ?
[Unregistered] cardiotoxicity
[anniegeorge] alright
[Unregistered] convulsions
[ppliutcm] coma
[Unregistered] which is the third one
[anniegeorge] Coma , Convlusions and cardiotoxicity
[Unregistered] right
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[Unregistered] whuch drug has the same moa as tca's
[ppliutcm] antipsychonic
[Unregistered] no
[Unregistered] cocaine
[anniegeorge] DOC in Tourettes ?
[Victor_E] cocoain
[Unregistered] haloperidol
[anniegeorge] PImozide
[Victor_E] cocaine does if considering illicit drugs
[Unregistered] its haloperidol
[anniegeorge] alright , I read this in Kaplan
[Unregistered] yeasp
[Unregistered] anyway guys iam going to bed
[anniegeorge] hmm , ok
[Unregistered] please wish mme best of luck as iam waiting for my step 1 results
[anniegeorge] WHAT !! ALL THE BEST !
[Unregistered] does any of u guys knwo abt the oasis trick
[Victor_E] i'm sure you'll do fine, you really know your stuff
[anniegeorge] GOsh , lucky you !
[anniegeorge] you will do great
[Unregistered] thank you
[Unregistered] thanks guys please oray for me
[Victor_E] yes, there are instuctions in the step 1 forum
[anniegeorge] yeah , don't forget to give us a feedback about your exam , what did they ask and stuff like that
[Victor_E] give me a sec and i'll find the link
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[anniegeorge] atleast tell us what you studied and how long
[Unregistered] i tried registering for the exam today \
[anniegeorge] and ?
11:30 PM [anniegeorge] did u learn the FA thoroughly ?
11:30 PM [anniegeorge] *)
11:30 PM [Unregistered] and it says u have passed and cannot register but i dont know how far this ionfo is correct so iam going to wait for the mail copy
11:31 PM [Victor_E] http://www.valuemd.com/usmle-step-1-...sis-trick.html
11:31 PM [anniegeorge] that means u passed and get on with it now !! CONGRATULATIONS
11:31 PM [Victor_E] thats for the oasis trick
11:31 PM [Unregistered] yes i did try this but wanbted to know if i should depend on this for sure
11:31 PM [Unregistered] is it 100%
11:32 PM [anniegeorge] are u going to tell us or what? About what you read and how many months and what q uestions you did etc.. ?
11:32 PM [anniegeorge] :cl
11:32 PM [Unregistered] cause my wife tried this and it says i have passed but we have not told anyone we know cause w e r waiting for the mailed score copy
11:32 PM [anniegeorge] gosh... I want to be there
11:32 PM [Unregistered] yes
11:32 PM [anniegeorge] in thatsame position
11:32 PM [Victor_E] wow, thats great news so far
11:32 PM [Unregistered] dont worry annie u will pass too
11:33 PM [anniegeorge] so answer my question please
11:33 PM [anniegeorge] how many times did u read Kaplan and FA ?
11:33 PM [Unregistered] do u guys knwo anyone who has done this oasis trick oassed and then got the oaasssse score card by mail
11:33 PM [Unregistered] i did not do kaplan
11:33 PM [anniegeorge] oh then ?
11:33 PM [Unregistered] i read the brs book for physio and patho
11:33 PM [anniegeorge] ok and ?
11:33 PM [ppliutcm] oasis is 100% as far as i know
11:33 PM [anniegeorge] Pharm , Micro , Anat?
11:33 PM [anniegeorge] BEhav ?
11:33 PM [Unregistered] i did goljan lecturees in patho
11:33 PM [anniegeorge] ok
11:34 PM [Unregistered] all high yiekld goljan
11:34 PM [anniegeorge] thats it ?
11:34 PM [Unregistered] bheav only brs
11:34 PM [anniegeorge] Questions ?
11:34 PM [Unregistered] ok oi will tell u guys in detail
11:34 PM [Unregistered] physio brs good first very less info
11:35 PM [anniegeorge] ok
11:35 PM [Unregistered] patho qiuite a few mistakes in first aid nothing like goljan for patho
11:35 PM [anniegeorge] alright
11:35 PM [Unregistered] phramac make sure u know first aid phram cold and u will master it
11:35 PM [Unregistered] beh avioral
11:35 PM [Unregistered] beh do brs and frist aid
11:36 PM [Unregistered] micro first aid is great
11:36 PM [anniegeorge] wow , ok
11:36 PM [Victor_E] thanks for the tips
11:36 PM [anniegeorge] Immuno ?
11:36 PM [Unregistered] immuno forst aid not that goods
11:36 PM [Unregistered] do ketzung jus tone reading
11:36 PM [anniegeorge] ok
11:37 PM [Unregistered] anat just fdo first aid
11:37 PM [anniegeorge] wow , thanks ,that helps
11:37 PM [Unregistered] but guys please do goljan hight yield it helps
11:37 PM [anniegeorge] 100 pgs stuff right ?
11:37 PM [Unregistered] and please do nto get into wrong advice there r a lot of guys giving wrong advice
11:37 PM [Unregistered] yes the 100 pages
11:37 PM [Victor_E] the 100 pg notes can be downloaded for free from the download section of valuemd
11:37 PM [anniegeorge] yeah
11:37 PM [Unregistered] i dint know that
11:38 PM [anniegeorge] yeah I did that last month
11:38 PM [anniegeorge] then Biochemm ?
11:38 PM [Unregistered] and guys if any one tries to act smart while studyoing anyone u knwo kjust avoid them vcause many giys give the wroing info
11:38 PM [Victor_E] heres the link http://www.valuemd.com/downloads.php?do=file&id=17
11:38 PM [anniegeorge] alright
11:38 PM [anniegeorge] where did u read Biochem and Mol bio from ?
11:39 PM [Unregistered] biochem lippincoott and then first aid but goljan high yoeld is very good for biochem that man is a genius
11:39 PM [anniegeorge] wow , thanks
11:39 PM [anniegeorge] I have not read his notes yet
11:39 PM [Unregistered] mol bio dont bothrer much no matte rhow much u read it sucks
11:39 PM [Unregistered] poplease do annie
11:39 PM [Victor_E] if you can, listen to his audios
11:39 PM [anniegeorge] yeah I think you guys are right , I will do justice to Goljan
11:39 PM [Unregistered] guusyus can i get some siuncere adc=vice for step 2 as i do nto knwo where to start form
11:40 PM Unregistered has left the chat.
11:40 PM [anniegeorge] ok what questions did u do ?
11:40 PM [anniegeorge] Q book and Q bank how many time ?
11:40 PM Unregistered has left the chat.
11:40 PM [Ammu] step 2-kaplan crush the boards,USME world qbook ,qbank
11:40 PM [Unregistered] iam back guys
11:41 PM [Unregistered] giuuys any advice on step 2
11:41 PM [anniegeorge] Unreg what questions did u do ?
11:41 PM [anniegeorge] how many times each I have just started on questions Q book
11:41 PM [Unregistered] hey u guys did not answer my qs
11:41 PM [Victor_E] goljan has some audio and notes for step 2 also
11:41 PM [Unregistered] ok
11:41 PM [Ammu] to unregistered-for step2 -kaplan, crush the boards,USMLE world,Qbook and q bank
11:41 PM [anniegeorge] Ammu says Step 2 Crush the boards
11:42 PM [Unregistered] do any of u know of anyone who tried the oasis trick
11:42 PM [Victor_E] crush step 2 is supposed to be great, also step 2 qbank
11:42 PM [anniegeorge] ok Ammu
11:42 PM [Unregistered] ok
11:42 PM [anniegeorge] no
11:42 PM [anniegeorge] Unreg what questions ?
11:42 PM [Victor_E] everyone who has tried the oasis trick that i know has been dead on
11:42 PM [Ammu] myself
11:42 PM [Ammu] for step 2
11:42 PM [Victor_E] for step 1
11:42 PM [Unregistered] so i just take this oasiis trick to be triue then
11:42 PM [Ammu] it worked for me
11:43 PM [Victor_E] nothing is for sure, but its very likely
11:43 PM [Unregistered] but u know guys till u sodnt see that actual score report in ur hand u really dont know
11:43 PM [anniegeorge] Unreg get some good sleep you passed man !
11:43 PM [Unregistered] ammu habve u cleard ur step 1
11:43 PM [Ammu] no appearing
11:43 PM [Unregistered] ok
11:43 PM [Unregistered] annie u guys r great to chat with
11:43 PM [anniegeorge] again unrge what q uestions did u do and how many times ?
11:43 PM [anniegeorge] please ?
11:43 PM [Unregistered] i did the q bank
11:44 PM [anniegeorge] Q book BSS , NMS ?
11:44 PM [Unregistered] i think it helps a lot
11:44 PM [anniegeorge] Just Q bank ?
11:44 PM [anniegeorge] how many time ?
11:44 PM [Unregistered] actually guys remember one thing no mateer how many wqs u do
11:44 PM [Unregistered] if u have not understood why u went wrong u will get it wrong again and again
11:44 PM [anniegeorge] you are right
11:45 PM [anniegeorge] I agree 100%
11:45 PM [Unregistered] the moment u understood it u will answer it everytime they ask u
11:45 PM [anniegeorge] yeah
11:45 PM [Unregistered] itsd liek guys
11:45 PM [Unregistered] a qs on leshnyhan syndeorome
11:45 PM [anniegeorge] alright thanks for all the gr8 advice and sleep peacefully
11:45 PM [Unregistered] u knwo its is hgprt def
11:45 PM [anniegeorge] all the best for the rest
11:45 PM [Unregistered] so they will twist and turn and then int he end ask u the same thing in ad differnt way
11:46 PM [anniegeorge] Goodnight all
11:46 PM [Victor_E] yes, thanks for the great tips
11:46 PM [anniegeorge] bye
11:46 PM anniegeorge has left the chat.
11:46 PM [erum] Victor_E what time y guys started tonight
11:46 PM [erum] i missed it
11:46 PM [Unregistered] good night all guys iam going to sleep too
11:46 PM [Unregistered] gl too all of you
11:46 PM [Victor_E] tonight was set back to 11:00 pm
11:46 PM [Victor_E] but normally at 10 pm
11:47 PM [Victor_E] goodnight unregistered and best of luck!
11:47 PM [erum] must be estern time
11:47 PM [Victor_E] yes, est
11:47 PM [Ammu] yes-east
11:47 PM [Unregistered] when r u guys having the nesxt chat and how would i knwo if there is a step 2 chat
11:47 PM [erum] cuz its 10 48 for me
11:47 PM [erum] now
11:47 PM [Ammu] look in step 2 forum
11:47 PM [Unregistered] ok does it say there
11:47 PM [Ammu] yes
11:48 PM [Victor_E] next chat is Tuesday Jan 24 ANTIMICROBIALS AND ANTICANCER
11:48 PM [Unregistered] u mena go to the step 2 subroom
11:48 PM [Ammu] yes
11:48 PM [Unregistered] ok thanks a lot good night
11:48 PM [Victor_E] no, the step 2 chat forum of valuemd to schedule the chat
11:48 PM [Unregistered] how do i get there ima new here actually
11:48 PM [erum] ok thanks
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11:49 PM [Victor_E] the step 2 stuff is at http://www.usmle.ca/step2.php
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11:49 PM [Unregistered] thankls a lot victor good night
11:49 PM erum has left the chat.
11:49 PM [Victor_E] good night everyone
11:49 PM [Victor_E] see you all in the next chat
11:50 PM totumito has left the chat.
11:50 PM [scubadoc] night all
11:50 PM [noon] 11 or 10
11:50 PM [Victor_E] it should be at 10:00 pm est . tonight was only exception
11:50 PM [noon] good
11:50 PM [Unregistered] thnals and gl to all of u
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11:51 PM [Victor_E] bye
11:51 PM [noon] bye
11:51 PM [scubadoc] i'll post transcipt
11:51 PM [scubadoc] bye
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