Welcome
Victor_E has joined the chat.
[feudist] i guess
[voodooMD] hello! anybody home?
[Unregistered] hello
[Unregistered] hello gehrig ,you were supposed to email me.I hope you remeber we had a long discussion on step 2 qs around 2 weeks from now
[Unregistered] Again you are not there....hmmmmmm...I miss you so much....you brighten up my life in a way you never imagined...I cant wait to tell you that story....Parag
[phenotype] anyone there
[phenotype] anyone know what is up with st.chris
[Unregistered] hello everyone
[Unregistered] hello yousef
[anniegeorge] pharm chat starts in 15 mins
[Victor_E] yousef, if you're looking for the pharm chat, its in the step 1 chat room. you can get there by selecting that room on right menu
Yousef has joined subroom: USMLE_Step_1
Now entering USMLE_Step_1 subroom.
Victor_E has joined subroom: USMLE_Step_1
9:58 PM [Victor_E] hi everyone!
9:58 PM [Yousef] thanks
9:58 PM [freak] hi victor and annie
9:59 PM [scubadoc] hi all
9:59 PM [anniegeorge] hif
9:59 PM [anniegeorge] everybody in time I see !
9:59 PM [anniegeorge] wow
10:00 PM [Victor_E] pumped and ready to go
10:00 PM [anniegeorge] did everybody finsh all 7 chapters ?
10:00 PM [anniegeorge] honsetly I barely got thro 5
10:00 PM [scubadoc] 7?? i thought it was cvs and renal. is that 7 chapters?
10:01 PM [anniegeorge] anyways lets start because I know for the rest of the materail you guys will have qs ready
10:01 PM [anniegeorge] yes yes
10:01 PM [anniegeorge] 7 CVS and renal
10:01 PM [anniegeorge] ok
10:01 PM [scubadoc] ok
10:01 PM [anniegeorge] Identify the point on the Cardiac AP where class 1 antiarrhythmics drugs act.
10:02 PM [anniegeorge] On Phase 0 . Class 1 slows or blocks phase 0 in fast response fibers.
10:02 PM [Victor_E] fast na channels
10:02 PM [anniegeorge] What happens during Phase 0 ?
10:02 PM [Victor_E] depol
10:02 PM [anniegeorge] oh my I jus changed my color
10:03 PM [anniegeorge] you r right
10:03 PM [anniegeorge] Na cannels open , Na enters the cell down its conc gradient (fast Ina) causing membrane dpolarization . Rate of Depol depends on the no Na channels that open which in turn depends on the RMP of the cell.
10:03 PM [Victor_E] i was changing my color too
10:03 PM [anniegeorge] On what phase does the Class III drugs exert its effects ?
10:03 PM [freak] phase 3
10:04 PM [Victor_E] K channels
10:04 PM [Victor_E] 3
10:04 PM [anniegeorge] Phase 3. yes yes
10:04 PM [anniegeorge] What is Phase 3?
10:04 PM [freak] k ch open
10:04 PM [anniegeorge] It is the REPOLARIZATION PHASE in which the delayed rectifier K+ current rapidly increases as Ca2+ current dies out because of time dependent channel inactivation.
10:04 PM [Victor_E] repol
10:04 PM [freak] repol
10:04 PM [anniegeorge] yes yes yes
10:04 PM [anniegeorge] What is Conductance ? What are it determinants ?
10:05 PM [Victor_E] speed of the spread of impulse
10:05 PM [anniegeorge] Conduction velocity… 3 major determinants : Rate of Phase0 depolarization—as Vmax decreases conduction velocity decreases Threshold Potential- the less negative the slower the conduction velocity Resting Potential : the more negative the RP the faster the conduction.
10:05 PM [anniegeorge] How can you depolarize a slow response fiber ?
10:05 PM [freak] pacemaker current
10:06 PM [anniegeorge] no
10:06 PM [anniegeorge] By activating the calcium channels ( Ica-L and Ica-T)
10:06 PM [anniegeorge] What class of Antiarrhythimcs exerts its action on the Phase 0 of slow response fibers ?
10:06 PM [anniegeorge] Class IV
10:06 PM [anniegeorge] What is the major distinctive feature of slow fibers ?
10:07 PM [Victor_E] sa and av nodes
10:07 PM [anniegeorge] here is where Freaks ans will be right
10:07 PM [freak] spontaneous depol
10:07 PM [anniegeorge] SPONTANEOUS depolarization ( the rising slope of phase 4 of AP in the diagram)… PACEMAKER POTENTIAL or pacemaker current. Pacemaker potential is a composite of inward Na (If) and Ca(Ica-T) currents and outward K+ currents (I Ka).
10:07 PM [anniegeorge] yes yes
10:07 PM [anniegeorge] :cl
10:07 PM [anniegeorge] What class of Antiarrhythmics exerts its effects on Phase 4 of slow fibers ?
10:08 PM [freak] 2 n 4
10:08 PM [anniegeorge] yes yes
10:08 PM [anniegeorge] Class II and Class IV
10:08 PM [anniegeorge] Define refractoriness.
10:09 PM [anniegeorge] The inability to respond to a stimulus- property of all cardiac muscles. Ratio of ERP to the APD is a measure of Refractoriness.
10:09 PM [Victor_E] inability to respond
10:09 PM [freak] inability to respond to stim
10:09 PM [anniegeorge] ERP ?
10:09 PM scubadoc has left the subroom.
10:09 PM [freak] no response ca n be elicited
10:09 PM [anniegeorge] correct
10:10 PM [anniegeorge] NO stimulus of any magnitude can elicit a response . Lasts into stage 3 of AP.
10:10 PM [anniegeorge] What drugs prolong ERP ?
10:10 PM [anniegeorge] Blockers of K+ channels prolong ERP
10:11 PM [anniegeorge] RRP?
10:11 PM [scubadoc] quinidine
10:11 PM [anniegeorge] no
10:11 PM [anniegeorge] yes yes
10:11 PM [freak] k ch bl
10:11 PM [freak] cl 3
10:11 PM [anniegeorge] Quinidine blocks K too
10:11 PM [anniegeorge] A strong stimulus can elicit a response but timing will be out of sync with the rest of the heart and arrhythmias may occur.
10:12 PM [anniegeorge] thaT is RRP
10:12 PM [anniegeorge] True or False ? SA node is innervated by both PANS And SANS
10:12 PM [freak] true
10:12 PM [anniegeorge] right
10:12 PM [anniegeorge] How does Beta 1 receptor activation and M2 receptor activation affect the Phase 4 slope?
10:13 PM [freak] increae, and dec respectively
10:13 PM [anniegeorge] yea right on
10:13 PM [anniegeorge] Beta 1 activation increases cAMP which will inturn inc upstroke velocity in pacemakers Shorten AP And Inc HR thus Increasing slope of Phase 4. M2 Receptor activation decreases cAMP which does the opp of the above plus slows the rate of diastolic depolarization and thus decrease HR
10:13 PM [anniegeorge] Name a group of drugs that prevent cAMP formation ?
10:14 PM [anniegeorge] Beta blockers !
10:14 PM [anniegeorge] What are the Class 1A antiarrhythmics ?
10:14 PM [freak] na ch bl
10:14 PM [Victor_E] quinidine, procainamide
10:14 PM [anniegeorge] right Vic
10:14 PM [anniegeorge] Quinidine , Procainamide
10:15 PM [anniegeorge] Mechanism of Action ?
10:15 PM [freak] bl fast na ch
10:15 PM [Victor_E] block fast Na channel
10:15 PM [anniegeorge] yea yeah yeah
10:15 PM [anniegeorge] V
10:15 PM [anniegeorge] Decreases Vmax by blocking fast Na channels Increases AP duration and ERP Block K channels and decrease inflow of Ca++
10:15 PM [anniegeorge] Quinidine additional effects ?
10:16 PM [freak] m bl
10:16 PM [Victor_E] inc ERP
10:16 PM [anniegeorge] M block Increase HR and AV conduction Vasodilation via ALPHA block –reflex tachycardia
10:16 PM [Victor_E] antichol
10:16 PM [freak] and k ch bl
10:16 PM [anniegeorge] Adverse effects ?
10:16 PM [Victor_E] cinchonism
10:16 PM [anniegeorge] yea
10:17 PM [Victor_E] hearing loss
10:17 PM [anniegeorge] no
10:17 PM [anniegeorge] N&V CINCHONISM Hypotension Torsades
10:17 PM [freak] prolongs qrs and inc qt int
10:17 PM [anniegeorge] yeah freak
10:17 PM [freak] hey any rx bl k ch czs torsades
10:17 PM Unregistered has left the chat.
10:17 PM [anniegeorge] What is Cinchonism ?
10:18 PM [anniegeorge] oh yeah
10:18 PM [freak] tinnitus
10:18 PM [anniegeorge] GI,Tinnitus, Ocular dysfunction,CNS excitation
10:18 PM [freak] its due to combo of m and alpha bl
10:19 PM [anniegeorge] yes yes
10:19 PM [anniegeorge] What is Cinchonism
10:19 PM [anniegeorge] what is Torsades ?
10:19 PM [Victor_E] flushed and sweaty skin
10:19 PM [anniegeorge] prolongation of QRS and inc QT
10:20 PM [anniegeorge] Drug interactions of Quinidine ?
10:20 PM Unregistered has left the chat.
10:20 PM [Victor_E] aggravates MG
10:20 PM [freak] disp dig,
10:20 PM [anniegeorge] yeah yeah
10:20 PM [anniegeorge] Hyperkalemia esp when pts are taking K substitutes Diplaces Digoxin from tissue binding sites enhancing toxicity Oppose actions of AChE inhibitors in My Gravis
10:21 PM [anniegeorge] Procainamide metabolism ?
10:21 PM [anniegeorge] Via n-acetyltransferase ( genotypic variation) to n-acetyl procainamide (NAPA) an active metabolite that prolongs APD. Less likely to occur with IV administration
10:21 PM [anniegeorge] Adverse effect seen in a slow acetylator ?
10:22 PM [anniegeorge] :gu
10:22 PM [anniegeorge] SLE like syndrome
10:22 PM [freak] sle like syn
10:22 PM [anniegeorge] Other side effects ?
10:22 PM [Victor_E] agranulocytoisis
10:22 PM [freak] hematotoxicity
10:22 PM [freak] torsades
10:22 PM [anniegeorge] yea yea yea yea !!
10:22 PM Unregistered has left the chat.
10:22 PM [anniegeorge] right on !
10:23 PM [anniegeorge] Thrombocytopenia , agranulocytosis , dizziness , hallucinations, Torsades
10:23 PM [anniegeorge] Class IB drugs?
10:23 PM [Victor_E] lidocaine
10:23 PM [Victor_E] phenytoin
10:23 PM [anniegeorge] Lidocaine, Phenytoin , Mixeletine , Tocainide
10:23 PM [anniegeorge] right on Victor
10:23 PM [anniegeorge] Clinical use of Lidocaine ?
10:24 PM [freak] iv in arr
10:24 PM [freak] post mi
10:24 PM [anniegeorge] yeah
10:24 PM [anniegeorge] IV- post MI, open heart surgery ,due to digitalis , DOC for arry following attempted cadioversion
10:24 PM [anniegeorge] Class II Action ?
10:24 PM [Victor_E] Beta blockers
10:24 PM [anniegeorge] yes yes
10:25 PM [anniegeorge] Action ?
10:25 PM [anniegeorge] Decrease SA and AV nodal activity of Beta Blockers Decrease in phase 4 of AP , Prevent B1 receptor activation which would normally increase cAMP
10:25 PM [freak] dec phase 4 of slow fib
10:25 PM [anniegeorge] yes yes action on lsow fibers
10:25 PM [anniegeorge] Clinical use ?
10:26 PM [Victor_E] prevention of sudden death in myocardial infarct
10:26 PM [freak] post mi, svts
10:26 PM Unregistered has left the chat.
10:26 PM [anniegeorge] yes thats right :box
10:26 PM [anniegeorge] Prophylaxis post MI and SVT
10:26 PM [anniegeorge] Use of Esmolol ?
10:26 PM [Victor_E] supravent arryth
10:26 PM [anniegeorge] IV In acute SVTs
10:27 PM [freak] iv is used in acute svt
10:27 PM [anniegeorge] yeah yeah
10:27 PM [anniegeorge] Class III drugs action ?
10:27 PM [Victor_E] k blockers
10:27 PM [anniegeorge] Increase APD and ERP Slow phase 3
10:27 PM [anniegeorge] yes yes vic
10:28 PM [anniegeorge] Class 3 drugs are ?
10:28 PM [Victor_E] amiodarone
10:28 PM Unregistered has left the chat.
10:28 PM [Victor_E] bretylium
10:28 PM [anniegeorge] thats right
10:28 PM [anniegeorge] Bretylium , Amiodarone ,Sotalol
10:28 PM [anniegeorge] Name a drug in this class that mimics action of drugs from all classes ?
10:28 PM [freak] way to go annie
10:28 PM Unregistered has left the chat.
10:29 PM [freak] amiodarone
10:29 PM [Victor_E] amiodarone
10:29 PM [anniegeorge] well my questions are coming to an end and I am going to make qs on the spot
10:29 PM [anniegeorge] well done
10:29 PM Unregistered has left the chat.
10:29 PM [freak] cool
10:29 PM [Victor_E] your questions are awesome annie
10:29 PM [anniegeorge] Adverse effects ?
10:29 PM [Victor_E] smuff skin for amiodarone
10:30 PM [anniegeorge] wow , you look like a smurf
10:30 PM [Victor_E] yep, you turn blue
10:30 PM [anniegeorge] Pul fibrosis, corneal deposits , smurf skin ,phototoxicity , thyroid dysfunction , increased LDL-C , torsades and hepatic necrosis
10:30 PM ppliutcm has left the chat.
10:30 PM [anniegeorge] what are class 4 drugs ?
10:31 PM [freak] ca ch blo
10:31 PM [Victor_E] veyapamil
10:31 PM [freak] verapamil
10:31 PM [Victor_E] diltiazem
10:31 PM [anniegeorge] where is its use contraindicated ?
10:31 PM [Victor_E] amlopidine
10:31 PM [anniegeorge] WPW sxyndrome
10:32 PM [anniegeorge] what is the DOC for Parr SVT ?
10:32 PM [freak] reentrant act or aberrant condn
10:32 PM [Victor_E] adenosine
10:32 PM [freak] right vic
10:33 PM [anniegeorge] yeah right on you guys know your stuff well
10:33 PM [anniegeorge] treatment for Torsades ?
10:33 PM [freak] hey annie define wpw syn
10:33 PM [freak] plz
10:33 PM [freak] mg+
10:33 PM [anniegeorge] well it is a type of heart block tpe 2 I think
10:33 PM [anniegeorge] second degree right
10:33 PM [anniegeorge] exact patho I do not know
10:34 PM [freak] no its different , i'll look it up
10:34 PM [anniegeorge] ok cool
10:34 PM [anniegeorge] shorten APD with durgs like Isoproternol...
10:34 PM [scubadoc] Accessory connections between the atrium and ventricle are the result of anomalous embryonic development of myocardial tissue bridging the fibrous tissues that separate the 2 chambers. Although dozens of locations for bypass tracts can exist in preexcitation, including atriofascicular, fasciculoventricular, intranodal, or nodoventricular, the most common bypass tract is an accessory atrioventricular (AV) pathway otherwise known as a Kent bundle. This is the anomaly seen in WPW syndrome. Conduction through a Kent bundle can be anterograde, retrograde, or both.
10:35 PM [freak] thnx scuba
10:35 PM [anniegeorge] never heard of the KENT bundle thanks freak
10:35 PM [anniegeorge] I mean Scuba
10:35 PM [scubadoc] no prob, quoted from emedicine
10:36 PM [freak] cool
10:36 PM [anniegeorge] aha.. cool , all this time I was thinking it was a second degree heart block congenital ,
10:37 PM [anniegeorge] name the sympathoplegics used in HTN rx ?
10:37 PM [freak] bbl, ccb
10:37 PM [freak] alpha bl
10:38 PM [Victor_E] methyldopa?
10:38 PM [anniegeorge] which drug is an Alpha activator ?
10:38 PM [anniegeorge] ywah freak and vic'
10:39 PM [anniegeorge] Methyldopa and Clonidine
10:39 PM Unregistered has left the chat.
10:39 PM [anniegeorge] which one of them is a prodrug ?
10:39 PM [freak] methyldopa
10:39 PM Unregistered has left the chat.
10:39 PM [Victor_E] methlydopa
10:39 PM [anniegeorge] yeah
10:39 PM [anniegeorge] Adverse effects are ?
10:40 PM [scubadoc] the unregistereds are hilarious, every time a new guest comes in, it knocks the other off
10:40 PM [Victor_E] pos coombs test
10:40 PM [Victor_E] hemolytic anemia
10:40 PM [anniegeorge] oh thats what it is... I am thinking people re checking up on us !
10:40 PM [anniegeorge] yeah thats right !
10:40 PM [anniegeorge] true or false alpha methyl is safe in pregnancy
10:40 PM [freak] lol,,,,,,,,, yeah they r
10:40 PM [Victor_E] true
10:41 PM [freak] yes its true
10:41 PM [anniegeorge] cool
10:41 PM [anniegeorge] what Alpha activator will you give to pts who are opiod or nicotine dependent ?
10:41 PM [Victor_E] clonidine
10:41 PM [anniegeorge] thats right
10:42 PM [freak] u go vic
10:42 PM [anniegeorge] Mechanism od Action of Reserpine ?
10:42 PM [freak] prev st of ne in granules
10:42 PM [Victor_E] depetes norepi
10:42 PM [anniegeorge] yeah right right lIppincotts !
10:43 PM [anniegeorge] side effect ?
10:43 PM [freak] depression
10:43 PM [Victor_E] ortho hypotension
10:43 PM [anniegeorge] yes and one more unique one
10:43 PM [anniegeorge] DEPRESSION !
10:44 PM [Victor_E] suicidal??
10:44 PM [freak] yes
10:44 PM [anniegeorge] yes yes yes yes
10:44 PM [anniegeorge] sad but true
10:44 PM [anniegeorge]
10:44 PM [Victor_E] is it central, peripheral, or both?
10:44 PM [anniegeorge] what is a Long QT syndrome ?
10:44 PM [anniegeorge] both !
10:44 PM [freak] both
10:44 PM [Victor_E] only one that has both central and peripheral
10:45 PM [Victor_E] good!!
10:45 PM [anniegeorge] thanks !
10:45 PM [Victor_E] is that the torsades??
10:45 PM [anniegeorge] long qt syndr ?
10:45 PM [anniegeorge] yeah Torsades is a result of that
10:46 PM [anniegeorge] mutation in the gene encoding K channels
10:46 PM [Victor_E] didn't know that one
10:46 PM [freak] grt annie, whats the source
10:46 PM [anniegeorge] good old KAPLAN !
10:47 PM [anniegeorge] side notes
10:47 PM [anniegeorge] I am pressed for time , no time for any other book
10:48 PM [Victor_E] kaplan is all you really need....maybe first aid too. goljan great for path
10:48 PM [freak] gotcha
10:48 PM [freak] right thats so right
10:48 PM [anniegeorge] name drugs that prolong QT that are not drugs used for the heart ?
10:49 PM [anniegeorge] Cisapride , TCA, Erythromycin ,Thioridazine
10:49 PM [anniegeorge] name specific arteriolar dilators ?
10:50 PM [freak] hydralazine
10:50 PM [freak] minoxidil
10:50 PM [freak] diazoxide
10:50 PM [anniegeorge] Diazoxise , Hydralizine ,Minoxidil right on FREAK !
10:50 PM [anniegeorge] Venular dilators ?
10:50 PM [freak] nitrates
10:51 PM [anniegeorge] nitrates cause what side effect beacause of its action ?
10:51 PM [Victor_E] headache
10:51 PM Unregistered has left the chat.
10:51 PM [erum] headache due to cn release
10:51 PM [anniegeorge] venular dilation , causes venous pooling and orthostaic hpotension
10:51 PM Unregistered has left the chat.
10:51 PM [erum] cn=cyanide
10:52 PM [erum] and hypotension
10:52 PM [anniegeorge] what are the alpha blockers used in HTN rx ?
10:53 PM [erum] prazosin
10:53 PM [Victor_E] the 3 sins?
10:53 PM [Victor_E] prazosin
10:53 PM [freak] osins
10:53 PM [anniegeorge] sure , no man has known a three greater sins
10:53 PM [Victor_E] terazosin
10:53 PM [Victor_E] dozazosin
10:53 PM [anniegeorge] one has use in BPH ?
10:53 PM [Victor_E] terazosin and dozazosin used in bph
10:53 PM [anniegeorge] but causes problems in the fairer sex ?
10:54 PM [freak] prazosin
10:54 PM [anniegeorge] yes yes you are right
10:54 PM [erum] terazosin
10:54 PM [anniegeorge] all right
10:54 PM [anniegeorge] one side effect that elderly dhould be warne about with Sin ?
10:54 PM [anniegeorge] warned about ?
10:55 PM [freak] first dose syncope
10:55 PM [anniegeorge] first dose syncope
10:55 PM [Victor_E] postural hypotension
10:55 PM [anniegeorge] right on freak !
10:55 PM [anniegeorge] true
10:55 PM [erum] hypotension
10:55 PM [erum] on ist dose
10:55 PM [anniegeorge] what ethinic group responds better to beta blockers ?
10:56 PM [freak] whites and the young
10:56 PM [Victor_E] agree
10:56 PM [anniegeorge] right on !
10:56 PM [erum] caucasian
10:56 PM [anniegeorge] adverse effects of Beta blockers ?
10:56 PM [Victor_E] insomnia, depression
10:56 PM [freak] sex dysfn
10:56 PM [erum] bradycardia
10:56 PM [anniegeorge] OH yeah !
10:56 PM [anniegeorge] :cl
10:56 PM [erum] chf
10:57 PM [anniegeorge] increase LDL
10:57 PM [anniegeorge] maybe a problem in Asthmatics
10:57 PM [erum] if non selective=asthma
10:57 PM [anniegeorge] Mechanism of Action of Nitroprusside ?
10:58 PM [anniegeorge] yes yes yes erum !
10:58 PM [erum] edrf
10:58 PM [freak] dec tpr via dilattion of both art and ven
10:58 PM [anniegeorge] via activation of Guanylyl cyclase
10:58 PM [anniegeorge] Metabolism of Hydralazine ?
10:59 PM [freak] inc cgmp
10:59 PM [erum] localreceptors at atreiies and viens
10:59 PM [erum] causing dilation
10:59 PM [freak] n-acetyltransferase
10:59 PM [Victor_E] NO
10:59 PM [anniegeorge] n-acetyltransferase.. yeah so what could happen in a slow acetylator ?
10:59 PM [Victor_E] production of NO.....no saying no ....lol
10:59 PM [freak] lol
10:59 PM [anniegeorge] is that a joke ?
11:00 PM [freak] sle like syn
11:00 PM [anniegeorge] yeah freak !
11:00 PM [erum] lupus like
11:00 PM [anniegeorge] :cl
11:00 PM [Victor_E] yes, i realized after i wrote NO in big letters
11:00 PM [anniegeorge] what reaction must Minoxidil undego to exert its action ?
11:01 PM [Victor_E] conjugation
11:01 PM [anniegeorge] thats always good , makes life easy for us,
11:01 PM [freak] sulfation
11:01 PM [anniegeorge] FREAK !!!
11:01 PM [anniegeorge] WOW
11:01 PM [Victor_E] must be converted from prodrug to active drug
11:01 PM [anniegeorge] freak why would you not want to use Minoxidil ?
11:01 PM [anniegeorge] yup Victor
11:01 PM [freak] hypertrichosis
11:01 PM [anniegeorge] yup and pulm HTN
11:01 PM [freak] pul htn
11:02 PM [erum] inc hair and pulmonary hyptn
11:02 PM [anniegeorge] hey my time is up.. you guys can go ahead and continue or next time we meet we can continue along with CNS
11:02 PM [freak] hey annie when r we meeting again
11:02 PM [anniegeorge] I have yet to cpmplete reading CVS portions
11:02 PM [freak] yeah me too
11:02 PM [Victor_E] same here
11:03 PM [anniegeorge] I have to look at teh schedule... listen huge favor ?
11:03 PM [anniegeorge] CAN WE START FRIDAY PHARM DISCUSSION AT 11:00 PM ?
11:03 PM [freak] sure no prob
11:03 PM [scubadoc] Friday Jan 20 CNS
11:03 PM [freak] okie dokie
11:03 PM [freak] gl
11:03 PM [freak] all
11:03 PM [Victor_E] sounds good to me
11:04 PM [erum] ok
11:04 PM [Victor_E] goodnight, see you all friday
11:04 PM [anniegeorge] next 18th
11:04 PM [anniegeorge] 11:00 PM ok ?
11:04 PM [anniegeorge] :box
11:04 PM [freak] so cns or cv
11:04 PM [erum] what topic
11:04 PM [anniegeorge] both , cannot prolong any further...
11:05 PM [anniegeorge] do I have permission to start at 11:00 PM
11:05 PM [Victor_E] ok, 11 sounds fine for me
11:05 PM [anniegeorge] or you guys can start at 10:00 PM and I will join at 11:00 PM
11:05 PM [freak] ok grt thanx annie/vic,,,,,,,,,,
11:05 PM [erum] ok for me
11:05 PM [freak] gnite all and gl
11:05 PM [scubadoc] 11:00pm is great
11:05 PM [anniegeorge] how about all the others in the room ?
11:05 PM [anniegeorge] say something
11:05 PM [freak] 11p fine for me too
11:05 PM [anniegeorge] ppliutum
11:05 PM [erum] tx cya on 18
11:05 PM [anniegeorge] erum see you
11:06 PM [erum] 11p
11:06 PM [anniegeorge] bye freak
11:06 PM [Victor_E] isn't today the 18th?
11:06 PM [freak] bye annie, gnite and gl
11:06 PM [anniegeorge] yeah 20th Friday
11:06 PM [ppliutcm] ok
11:06 PM [anniegeorge] I need that
11:06 PM [Unregistered] what topics
11:06 PM [anniegeorge] Yousef what do you thiknk 11:00 Pm
11:06 PM [anniegeorge]
11:06 PM [freak] annie if any changes just email me
11:06 PM [scubadoc] topics are CV and CNS pharm from kaplan
11:07 PM freak has left the chat.
11:07 PM [anniegeorge] 11:00 PM i have Bible study before that
11:07 PM [anniegeorge] yeah yeah
11:07 PM [anniegeorge] ok good night guys
11:07 PM anniegeorge has left the chat.
11:07 PM [Victor_E] good night
11:07 PM [erum] bye
11:07 PM erum has left the chat.
11:07 PM [scubadoc] bye
11:07 PM scubadoc has left the chat.
11:08 PM [Unregistered] *)

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