01/6/05 15:13:06 [USMLE_Step_1] usmle_guy: hi clover
01/6/05 15:13:21 [USMLE_Step_1] clover: hello usmle guy
01/6/05 15:13:55 [USMLE_Step_1] usmle_guy: did the meeting time change or something?
01/6/05 15:14:10 [USMLE_Step_1] clover: not sure, i think people are just late today
01/6/05 15:15:14 [USMLE_Step_1] clover: today is neoplasia and RBCs and WBCs. is that right?
01/6/05 15:15:31 [USMLE_Step_1] usmle_guy: yes, i think so
01/6/05 15:16:47 [USMLE_Step_1] usmle_guy: we can get started and wait for others, or do you want to try again for tomorrow?
01/6/05 15:17:16 [USMLE_Step_1] clover: i dont mind going over a little bit of it to see if others come late.
01/6/05 15:17:27 [USMLE_Step_1] usmle_guy: ok, first neoplasia
01/6/05 15:17:33 [USMLE_Step_1] clover: ok
01/6/05 15:18:51 [USMLE_Step_1] usmle_guy: what is the #1 contributory factor responsible for cancer in US? (this is also the #2 cause of death in US)
01/6/05 15:19:03 [USMLE_Step_1] clover: smoking
01/6/05 15:19:10 [USMLE_Step_1] usmle_guy: yes, smoking
01/6/05 15:19:52 [USMLE_Step_1] usmle_guy: whats the main difference between malignant and benign tumors?
01/6/05 15:20:21 [USMLE_Step_1] clover: malignant invades and metastasizes
01/6/05 15:20:38 [USMLE_Step_1] usmle_guy: yes, there are some exceptions, but for the most part that is correct
01/6/05 15:21:10 [USMLE_Step_1] clover: exceptions are basal cell carcinoma and glioblastoma
01/6/05 15:21:18 [USMLE_Step_1] usmle_guy: yes, thats correct
01/6/05 15:22:03 [USMLE_Step_1] usmle_guy: what is the most common sarcoma in children? what about adults?
01/6/05 15:22:52 [USMLE_Step_1] clover: child = embryonal rhabdosarcoma. adult=malignant fibrous histiocytoma
01/6/05 15:23:00 [USMLE_Step_1] usmle_guy: yes, thats correct!
01/6/05 15:23:37 [USMLE_Step_1] usmle_guy: what is MC leukemia in children? adults?
01/6/05 15:24:07 [USMLE_Step_1] clover: children = ALL , adults = CLL
01/6/05 15:24:28 [USMLE_Step_1] usmle_guy: yes. CLL is also the most common overall leukemia
01/6/05 15:24:55 hutals Logs in
01/6/05 15:24:59 hutals Joins Subroom USMLE_Step_1
01/6/05 15:25:09 [USMLE_Step_1] usmle_guy: hi hutals
01/6/05 15:25:17 [USMLE_Step_1] clover: hello hutals
01/6/05 15:25:28 [USMLE_Step_1] hutals: hey there
01/6/05 15:25:53 [USMLE_Step_1] hutals: where is everyone? i thought the new chats were at 3 eastern?
01/6/05 15:26:14 [USMLE_Step_1] usmle_guy: i thought so too, but wasnt here yesterday, so maybe they were moved?
01/6/05 15:26:31 zoya Logs in
01/6/05 15:26:48 zoya Joins Subroom USMLE_Step_1
01/6/05 15:26:51 [USMLE_Step_1] hutals: i stopped by to say hi to some old friends and see how theyre doing. i guess i'll try back.
01/6/05 15:27:03 [USMLE_Step_1] usmle_guy: ok, bye hutals
01/6/05 15:27:07 [USMLE_Step_1] zoya: hi
01/6/05 15:27:09 [USMLE_Step_1] hutals: bye
01/6/05 15:27:20 hutals Logs Out
01/6/05 15:27:27 [USMLE_Step_1] usmle_guy: hi zoya
01/6/05 15:27:35 [USMLE_Step_1] clover: hello zoya
01/6/05 15:28:07 [USMLE_Step_1] clover: we're discussing neoplasia. welcome to join us
01/6/05 15:28:12 [USMLE_Step_1] zoya: ok
01/6/05 15:28:47 [USMLE_Step_1] usmle_guy: what term is given to neoplam derived from all three germ layers?
01/6/05 15:29:04 [USMLE_Step_1] zoya: teratoma
01/6/05 15:29:05 [USMLE_Step_1] clover: teratomas
01/6/05 15:29:14 [USMLE_Step_1] usmle_guy: yes, both correct
01/6/05 15:30:13 [USMLE_Step_1] usmle_guy: what neoplam will have a t8;14?
01/6/05 15:30:40 [USMLE_Step_1] clover: burkitts lymphoma
01/6/05 15:30:48 [USMLE_Step_1] zoya: burkitt's
01/6/05 15:31:07 rll322 Logs in
01/6/05 15:31:08 rll322 Joins Subroom USMLE_Step_1
01/6/05 15:31:14 [USMLE_Step_1] usmle_guy: yes, its burkitts which should not be confused with t14;18 for B cell follicular lymphoma
01/6/05 15:31:38 rll322 Logs Out
01/6/05 15:32:46 [USMLE_Step_1] usmle_guy: for neurofibromas, which one is located on chromosome 17 and which on chrom 22?
01/6/05 15:33:11 [USMLE_Step_1] clover: chrom 22 = NF2
01/6/05 15:33:30 [USMLE_Step_1] zoya: nf-1 is17
01/6/05 15:34:04 [USMLE_Step_1] usmle_guy: yes, notice the "2" in both chrom "22" and NF "2". notice the "1" in both NF"1" and chrom "1"7.
01/6/05 15:34:04 [USMLE_Step_1] zoya: nf-2 is22
01/6/05 15:34:23 [USMLE_Step_1] zoya:

01/6/05 15:34:34 [USMLE_Step_1] clover: good way to remember

01/6/05 15:34:49 [USMLE_Step_1] zoya: tumor associated with nf2
01/6/05 15:35:43 [USMLE_Step_1] usmle_guy: i know you will have bilateral hearing loss
01/6/05 15:36:24 [USMLE_Step_1] zoya: acoustic neuromas,meningiomas
01/6/05 15:36:46 [USMLE_Step_1] usmle_guy: thanks, couldnt remember
01/6/05 15:37:32 [USMLE_Step_1] zoya:

01/6/05 15:37:32 deaboletto Logs in
01/6/05 15:37:34 [USMLE_Step_1] usmle_guy: what is the tumor marker for testicular cancers?
01/6/05 15:37:45 deaboletto Joins Subroom USMLE_Step_1
01/6/05 15:37:51 [USMLE_Step_1] deaboletto: hi
01/6/05 15:37:54 [USMLE_Step_1] usmle_guy: hi deaboletto
01/6/05 15:38:05 [USMLE_Step_1] clover: hello deabo
01/6/05 15:38:10 [USMLE_Step_1] zoya: AFP
01/6/05 15:38:22 [USMLE_Step_1] zoya: hi
01/6/05 15:38:30 [USMLE_Step_1] clover: afp, hCG
01/6/05 15:38:41 [USMLE_Step_1] usmle_guy: yes, both correct
01/6/05 15:39:14 [USMLE_Step_1] usmle_guy: what is the tumor marker for multiple mylenoma?
01/6/05 15:39:15 katas Logs in
01/6/05 15:39:26 [USMLE_Step_1] clover: BJ proteins
01/6/05 15:39:48 katas Logs Out
01/6/05 15:40:13 [USMLE_Step_1] usmle_guy: yes, bence jones proteins which are lite chains in urine
01/6/05 15:40:23 [USMLE_Step_1] zoya: yes
01/6/05 15:40:37 [USMLE_Step_1] usmle_guy: what is the tumor marker for for serface derived ovarian caners?
01/6/05 15:40:57 [USMLE_Step_1] clover: CA125
01/6/05 15:41:17 [USMLE_Step_1] zoya: ca125
01/6/05 15:41:27 [USMLE_Step_1] usmle_guy: yes both correct!
01/6/05 15:41:43 [USMLE_Step_1] zoya: not very sepecific
01/6/05 15:42:06 [USMLE_Step_1] usmle_guy: i agree, not very specific
01/6/05 15:42:21 [USMLE_Step_1] zoya: CA19-9
01/6/05 15:42:30 [USMLE_Step_1] usmle_guy: same with PSA for prostate cancer, not very specific
01/6/05 15:42:43 [USMLE_Step_1] zoya: yes
01/6/05 15:42:57 [USMLE_Step_1] usmle_guy: 19-9 is for pancreatic carcinoma
01/6/05 15:43:06 [USMLE_Step_1] clover: pancreas
01/6/05 15:43:11 katas Logs in
01/6/05 15:43:17 [USMLE_Step_1] zoya: is an eecellent marker
01/6/05 15:43:36 [USMLE_Step_1] zoya: excellent ..i mean
01/6/05 15:43:43 katas Joins Subroom USMLE_Step_1
01/6/05 15:43:59 [USMLE_Step_1] katas: hi
01/6/05 15:44:14 [USMLE_Step_1] zoya: hi katas
01/6/05 15:44:16 [USMLE_Step_1] clover: what is the most common cancer incidence in men? (name top 3)
01/6/05 15:44:23 [USMLE_Step_1] clover: hello kitas
01/6/05 15:44:30 [USMLE_Step_1] usmle_guy: hi kitas
01/6/05 15:44:48 [USMLE_Step_1] deaboletto: prostate lung
01/6/05 15:45:13 [USMLE_Step_1] usmle_guy: prostate, lung, colon
01/6/05 15:45:37 [USMLE_Step_1] clover: yep, prostate, lung, colorectal
01/6/05 15:45:40 [USMLE_Step_1] deaboletto: hey guys i am listening to the audio but i dont know which day are u at in the 5 days
01/6/05 15:45:59 [USMLE_Step_1] deaboletto: colorectal more in chineese male
01/6/05 15:46:00 [USMLE_Step_1] clover: we're on the neoplasia chapter today
01/6/05 15:46:20 [USMLE_Step_1] deaboletto: ok what day acc to glgan
01/6/05 15:46:42 [USMLE_Step_1] zoya: most
01/6/05 15:46:45 katas Logs Out
01/6/05 15:46:46 [USMLE_Step_1] clover: not sure of day, but also doing RBCs and WBCs
01/6/05 15:47:00 [USMLE_Step_1] deaboletto: u know where to get the goljan book or it has differnt name
01/6/05 15:47:04 [USMLE_Step_1] deaboletto: i didnt find it
01/6/05 15:47:23 [USMLE_Step_1] clover: my guess is around 2 to 3rd day
01/6/05 15:47:35 [USMLE_Step_1] deaboletto: did u guys finish the inflamm and hemody
01/6/05 15:47:51 [USMLE_Step_1] usmle_guy: i wasnt here yesterday, so not sure
01/6/05 15:48:04 [USMLE_Step_1] zoya: you can try to find it at half.com, barnes and noble
01/6/05 15:48:07 [USMLE_Step_1] deaboletto: that is the 2nday the neo and hema\
01/6/05 15:48:15 [USMLE_Step_1] usmle_guy: i know we did most of inflam on tues
01/6/05 15:48:22 [USMLE_Step_1] deaboletto: ok
01/6/05 15:48:41 [USMLE_Step_1] deaboletto: so any clue about the goljan notes
01/6/05 15:48:50 [USMLE_Step_1] zoya: e bay
01/6/05 15:49:04 [USMLE_Step_1] deaboletto: as i am writing after him which is crazy the guy is so fast
01/6/05 15:49:13 [USMLE_Step_1] deaboletto: i mean new ones
01/6/05 15:49:26 [USMLE_Step_1] usmle_guy: agree, ebay is the best bet for the full notes. for the hightyields can download from here
01/6/05 15:49:48 [USMLE_Step_1] deaboletto: how big is the high yield
01/6/05 15:49:51 karanbeta Logs in
01/6/05 15:49:51 karanbeta Joins Subroom USMLE_Step_1
01/6/05 15:49:53 [USMLE_Step_1] deaboletto: is that 35 pages
01/6/05 15:50:07 [USMLE_Step_1] usmle_guy: i would imagine its alot easier to follow with the notes than to try to take notes
01/6/05 15:50:25 karanbeta Logs Out
01/6/05 15:50:30 [USMLE_Step_1] usmle_guy: yes, the 36 pg high yields available in download section
01/6/05 15:51:05 [USMLE_Step_1] deaboletto: but i have them..they are differnt than what he is saying
01/6/05 15:51:22 [USMLE_Step_1] deaboletto: it seema that the book is very rich
01/6/05 15:51:36 [USMLE_Step_1] clover: what is the most common incidence of cancers in women (top 3)
01/6/05 15:51:43 [USMLE_Step_1] deaboletto: braEST ,,
01/6/05 15:51:49 [USMLE_Step_1] deaboletto: ENDOMETRIAL..
01/6/05 15:51:51 [USMLE_Step_1] deaboletto: THYROID
01/6/05 15:51:54 [USMLE_Step_1] usmle_guy: breast, lung, colon
01/6/05 15:52:09 [USMLE_Step_1] zoya: breast lung colon
01/6/05 15:52:26 [USMLE_Step_1] clover: yes, breast lung colorectal
01/6/05 15:52:36 [USMLE_Step_1] deaboletto: catch u later guys as i didnt listen yet to neoplasms,,
01/6/05 15:52:43 [USMLE_Step_1] deaboletto: thanx for yr support
01/6/05 15:52:48 [USMLE_Step_1] deaboletto: later
01/6/05 15:52:58 [USMLE_Step_1] zoya: ok,bye
01/6/05 15:52:59 deaboletto Logs Out
01/6/05 15:53:25 [USMLE_Step_1] clover: most deadly cancers for men? women?
01/6/05 15:53:53 [USMLE_Step_1] zoya: lung
01/6/05 15:54:05 [USMLE_Step_1] usmle_guy: men is lung, prostate, colon. women is lung, breast, colon
01/6/05 15:54:24 [USMLE_Step_1] clover: yes, lung is first for both
01/6/05 15:54:57 [USMLE_Step_1] usmle_guy: what is MC cancer in SE china?
01/6/05 15:55:20 [USMLE_Step_1] clover: stomach cancer from smoked fish
01/6/05 15:55:57 [USMLE_Step_1] usmle_guy: no, thats in Japan
01/6/05 15:56:22 [USMLE_Step_1] zoya: stomach cancer in japan
01/6/05 15:56:30 [USMLE_Step_1] clover: oh, sorry. then its nasopharygeal carcinoma because of EBV
01/6/05 15:56:51 [USMLE_Step_1] zoya: yes
01/6/05 15:56:53 [USMLE_Step_1] usmle_guy: yes, thats correct
01/6/05 15:57:25 [USMLE_Step_1] usmle_guy: whats the MC cancer prevented by immunization?
01/6/05 15:57:52 [USMLE_Step_1] zoya: hepatocellular ca
01/6/05 15:57:54 [USMLE_Step_1] clover: hepatocellular
01/6/05 15:58:25 [USMLE_Step_1] usmle_guy: yes, because some prevention by HBV
01/6/05 15:59:12 [USMLE_Step_1] usmle_guy: has anyone heard from roxanita?
01/6/05 15:59:29 [USMLE_Step_1] clover: not since the first chat
01/6/05 16:00:38 [USMLE_Step_1] zoya: inactivation of APC results in
01/6/05 16:00:45 [USMLE_Step_1] usmle_guy: what are the risk factors for breat adenocarcinoma?
01/6/05 16:01:10 [USMLE_Step_1] usmle_guy: familial polyposis
01/6/05 16:01:17 [USMLE_Step_1] zoya: also
01/6/05 16:01:52 [USMLE_Step_1] clover: i think also lung, stomach cancer
01/6/05 16:01:53 [USMLE_Step_1] zoya: esophageal and gastric ca
01/6/05 16:03:02 [USMLE_Step_1] clover: age, unapposed estrogen, history of endometrial ca, high fat low fiber diet, family history
01/6/05 16:04:09 [USMLE_Step_1] usmle_guy: yes, thats correct. but dont forget the most obvious which is breast cancer in other breast as a risk factor

01/6/05 16:05:17 [USMLE_Step_1] usmle_guy: what phase of cell cycle do antimetabolites work?
01/6/05 16:05:35 [USMLE_Step_1] clover: s phase
01/6/05 16:06:03 [USMLE_Step_1] usmle_guy: yes, s phase. what about bleomycin?
01/6/05 16:06:23 [USMLE_Step_1] clover: bleomycin is g2 phase i think
01/6/05 16:06:39 mmw Logs in
01/6/05 16:06:39 mmw Joins Subroom USMLE_Step_1
01/6/05 16:06:48 [USMLE_Step_1] usmle_guy: yes, g2 phase is correct
01/6/05 16:06:53 [USMLE_Step_1] usmle_guy: hi mmw
01/6/05 16:07:00 [USMLE_Step_1] zoya: hi mmw
01/6/05 16:07:03 [USMLE_Step_1] clover: hello mmw
01/6/05 16:07:05 [USMLE_Step_1] mmw: hi
01/6/05 16:07:14 [USMLE_Step_1] mmw: how r u today
01/6/05 16:07:27 [USMLE_Step_1] zoya: 15;17 translocation
01/6/05 16:07:34 [USMLE_Step_1] clover: good, just talking about neoplasia
01/6/05 16:07:42 [USMLE_Step_1] zoya: good
01/6/05 16:08:11 [USMLE_Step_1] mmw: i have an appoinment today i have to go now i just wanted to say hi and see u tomorrow
01/6/05 16:08:32 [USMLE_Step_1] mmw: bye zoya,usmle and clover
01/6/05 16:08:37 [USMLE_Step_1] zoya: see you tomorrow, bye
01/6/05 16:08:47 [USMLE_Step_1] mmw: have a nice study
01/6/05 16:08:50 [USMLE_Step_1] usmle_guy: ok, see you tomorrow
01/6/05 16:08:58 mmw Logs Out
01/6/05 16:09:42 [USMLE_Step_1] clover: acute promyelocytic leukaemia
01/6/05 16:09:49 [USMLE_Step_1] zoya: yes
01/6/05 16:10:08 [USMLE_Step_1] zoya: what is thtreatment?
01/6/05 16:10:42 shmily Logs in
01/6/05 16:11:17 shmily Joins Subroom USMLE_Step_1
01/6/05 16:11:18 [USMLE_Step_1] clover: FFP and platelets
01/6/05 16:11:22 [USMLE_Step_1] zoya: retinoic acid analogu all-transretinoic acid...
01/6/05 16:11:31 [USMLE_Step_1] clover: daunorubicin and cytarabine
01/6/05 16:11:36 [USMLE_Step_1] zoya: anlogue
01/6/05 16:11:42 shmily Logs Out
01/6/05 16:12:09 [USMLE_Step_1] usmle_guy: interesting, i didnt know that
01/6/05 16:12:31 [USMLE_Step_1] zoya: results in maturation of the cells and clinical remission
01/6/05 16:13:11 [USMLE_Step_1] clover: what complication can cyclophosphamide cause and how can it be blocked?
01/6/05 16:13:42 [USMLE_Step_1] usmle_guy: hemorrhagic cystitis which can be blocked by mesna
01/6/05 16:14:16 [USMLE_Step_1] clover: yes
01/6/05 16:14:29 [USMLE_Step_1] zoya: i forgot that one.thanks
01/6/05 16:14:51 [USMLE_Step_1] clover: what is a GnRH analog used for treatment of prostate cancer?
01/6/05 16:15:18 [USMLE_Step_1] usmle_guy: leuprolide
01/6/05 16:15:41 [USMLE_Step_1] clover: yes
01/6/05 16:16:37 [USMLE_Step_1] clover: both AFP and B-hCG are most likely to be elevated in which primary tumor site? lung, testicle, liver, colon, or ovary
01/6/05 16:17:23 [USMLE_Step_1] zoya: ovary/testes?
01/6/05 16:17:42 [USMLE_Step_1] usmle_guy: i'd guess testicle, but ovary looks tempting too
01/6/05 16:17:57 [USMLE_Step_1] clover: yes, its testicular cancer
01/6/05 16:18:41 [USMLE_Step_1] zoya: ok
01/6/05 16:19:31 [USMLE_Step_1] usmle_guy: a tumor that could potentially produce cushings syndrome and hyponatremia is most likely located in the .... kidney, placenta, liver, thryroid, or lung?
01/6/05 16:20:04 [USMLE_Step_1] zoya: lung
01/6/05 16:20:09 [USMLE_Step_1] usmle_guy: small cell ca of lung
01/6/05 16:20:33 [USMLE_Step_1] clover: yes
01/6/05 16:21:59 [USMLE_Step_1] clover: which of folling is most common cancer and cancer killer in men and women? malignant melanoma, lung, colorectal, malignant lymphoma, or stomach cancer?
01/6/05 16:22:23 [USMLE_Step_1] zoya: lung
01/6/05 16:22:25 clover Logs Out
01/6/05 16:22:40 clover Logs in
01/6/05 16:22:47 clover Joins Subroom USMLE_Step_1
01/6/05 16:23:00 [USMLE_Step_1] clover: oops, i'm back
01/6/05 16:23:07 [USMLE_Step_1] clover: i mean 2nd most common in both
01/6/05 16:23:21 [USMLE_Step_1] usmle_guy: lung
01/6/05 16:23:26 [USMLE_Step_1] zoya: colon
01/6/05 16:23:42 [USMLE_Step_1] usmle_guy: lung is 1st and colon is 2nd i think
01/6/05 16:23:48 [USMLE_Step_1] zoya: 2nd most is colon
01/6/05 16:24:17 [USMLE_Step_1] clover: sorry for confusion. yes, lung is most common for both and colon is 2nd for both
01/6/05 16:24:40 [USMLE_Step_1] clover: individually it would be a different story
01/6/05 16:24:48 [USMLE_Step_1] zoya: which oncogenes are activated by way of amplification?
01/6/05 16:25:17 [USMLE_Step_1] clover: i think we finished neoplasia
01/6/05 16:25:36 [USMLE_Step_1] usmle_guy: yes, we hit the most important points
01/6/05 16:26:04 [USMLE_Step_1] usmle_guy: should we call it quits early since only three of us, or should we move onto next chapter?
01/6/05 16:27:07 [USMLE_Step_1] clover: i dont care either way. what do you think zoya
01/6/05 16:27:27 [USMLE_Step_1] zoya: i have to leave early today......
01/6/05 16:27:33 [USMLE_Step_1] zoya: sorry
01/6/05 16:27:52 [USMLE_Step_1] clover: sounds good to me because i haven't finished that chapter anyway

01/6/05 16:28:05 [USMLE_Step_1] usmle_guy: ok, so i'll see you both tomorrow
01/6/05 16:28:10 [USMLE_Step_1] zoya:

01/6/05 16:28:25 [USMLE_Step_1] clover: bye zoya and usmle guy
01/6/05 16:28:33 [USMLE_Step_1] usmle_guy: bye
01/6/05 16:28:40 [USMLE_Step_1] zoya: ok, it was nice chatting with you
01/6/05 16:28:45 [USMLE_Step_1] zoya: bye
01/6/05 16:28:48 usmle_guy Logs Out
01/6/05 16:28:57 clover Logs Out
01/6/05 16:29:00 zoya Logs Out
01/6/05 16:32:59 acestep1 Logs in
01/6/05 16:34:13 acestep1 Logs Out