gallbladder contraction following a fatty meal

[Cortez]

Which of the following hormones is most important in the initiation of gallbladder contraction following a fatty meal?

A. CCK
B. Gastrin
C. GIP
D. Secretin
E. VIP

[Asclepius1]

CCK..it is responsible for contraction of bile duct and secretion of bile..

[OLM]

Agree. answer is cck.

CCK causes the pancreas to grow and to produce the enzymes of pancreatic juice, and it causes the gallbladder to empty.

[Cortez]

The correct answer is A. Cholecystokinin, or CCK, is synthesized in the duodenal and jejunal mucosa and stimulates gallbladder contraction and pancreatic enzyme secretion. Other functions include slowing of gastric emptying, an atrophic effect on the pancreas, and secretion of antral somatostatin, which in turn, decreases gastric acid secretion.

Gastrin (choice B) prepares the stomach and small intestine for food processing, including stimulating secretion of HCl, histamine, and pepsinogen, increasing gastric blood flow, lower esophageal sphincter tone, and gastric contractions.

Gastric inhibitory peptide, or GIP (choice C), stimulates pancreatic insulin secretion at physiologic doses and inhibits gastric acid secretion and gastric motility at pharmacologic doses.

Secretin (choice D) stimulates secretion of bicarbonate-containing fluid from the pancreas and biliary ducts.

Vasoactive intestinal polypeptide, or VIP (choice E), relaxes intestinal smooth muscle and stimulates gut secretion of water and electrolytes.