Mechanism of Pain in Myocardial Infarct?

[winston]

Pain associated with myocardial infarction is due to:
a) Increase Sympathetic
b) Increase Parasympathetic
c) Increase Diastolic Pressure
d) Increase Systolic Pressure?
e) Increase in toxic metabolites in the heart

I don't know the answer but i was thinking an increase in sypmathetic activity......if anyone knows for sure please post the best answer since ithink this is a fairly high yield concept.

Thanks!

[beefy]

Originally Posted by winston

Pain associated with myocardial infarction is due to:
a) Increase Sympathetic
b) Increase Parasympathetic
c) Increase Diastolic Pressure
d) Increase Systolic Pressure?
e) Increase in toxic metabolites in the heart

I don't know the answer but i was thinking an increase in sypmathetic activity......if anyone knows for sure please post the best answer since ithink this is a fairly high yield concept.

Thanks!

answer e

"Although several substances have been investigated as potential mediators of anginal pain, at present only two molecules have been convincingly demonstrated to be involved in the genesis of cardiac ischemic pain in man: adenosine and bradykinin....As bradykinin is released in large amounts by the heart during ischemia, it can be a natural stimulus for causing, via arachidonic acid metabolites, excitation of the sensory receptors signaling pain during myocardial ischemia."

the other answers don't really directly correlate to pain in my opinion..