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cell receptors
[quote=latkan;548170]13. Compare the cellular localisation and function of receptors for steroid and hydrophilic peptide hormones. Give 2 examples for each hormone
This has to do with whether the hormone can cross the cell membrane. Cell membranes are mostly lipids, right. If it is lipid soluble, i.e., steroid, it crosses the membrane and the receptors are in the nucleus. If it is hydrophillic/nonlipic it cannot cross the cell membrane so attaches on the receptor which is on the surface of the cell. After the hormone binds to the receptor it sets off chemical cascades in the cell which also influence cellular activity in the nucleus. This is where second messengers and G-proteins come into play.
Steroids would be an example of hormones which cross the cell membrane and the receptors are inside cell. Insulin is an example of a molecule with receptors on the cell surface. You should be able to figure out the rest or at least what to search for. This would be found in biochem or cell biology textbooks. Maybe physiology texts also.
Hope this helps. I'm going from memory, hope this is all right.
Last edited by lmoliver; 01-21-2007 at 11:49 PM.
Reason: change a word
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