Adaptation to high altitude LUNGS

[IMG SURVIVOR]

So what are the changes that occur in high altitude related to:

1-ALVEOLAR Po
2-Pulmonary vessels
3- to 2-3 DPG concentration
4-ventilation
5-Hemoglobin












1-Will decrease because of the barometric pressure is decrease= HYPOXEMIA

2-VASOCONSTRICTION

3-they will be increased shifting the hemoglobin O curve to the right

4- Hyperventilation
5-You will have polycythemia because hypoxia will stimulate the kidney to release erythroproietin

[stateofequilibrium]

say that 10x fast! Keep up the good work, some good review.

[IMG SURVIVOR]

Thank you state of estateofquilibrium or may I say HOMOESTASIS

[elektra]

Remeber that 3 factors determine alveolar PO2
1-Atmospheric pressure
2-Concentration of O2
3- PA CO2

I like this formula to see what happend to Alveolar Po2

PAO2 = (Patm-PH2O) FO2-PACO2/ R

Patm= at sea level is 760 mmHg (changes occur with going to a place to high altittude or diving)
PH2O= 47 mmHg
FO2= Fraction of oxigen inspired, at room air = 0.21 (giving supplemental O2 will increase FO2)
PACO2= alveolar pressure of CO2 = 40 mmHg
R= Is the respiratory exchange ratio wich normally is 0.8

So it is so simple only follow the formula

a Increase of PCO2 will decrese the PAO2
a decrease in atmospheric pressure (high alttitude) will decrese the PAO2
a increase of inspire oxigen concentration will increase PAO2

[IMG SURVIVOR]

Very Good Reply