I'm looking for selective receptor probes that produce a behavioural output (for example the hypothermic response produced by the 5-HT1a agonist 8-OH-DPAT). I'm looking for probes to investigate receptor desensitisation following chronic antidepressant treatment in rats. I've identified some receptors of interest and the selective agonists for these receptors but have no information on what behavioural or physiological output activation of these receptors would produce, if any. For example, the sigma σ1 receptor. Are there any papers on reliable probes for these kind of studies? Or if anyone here has any information it would be greatly appreciated. Thanks