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  1. #1
    IMG SURVIVOR's Avatar
    IMG SURVIVOR is offline Moderator 527 points
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    Pharmacology Question

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    A 68-year-old man has stable mild exertional angina. He underwent coronary artery bypass graft surgery 2 years ago. His heart rate is 60/min, blood pressure is 120/60mm Hg, and left ventricular function and hemoglobin are normal. He takes maximally tolerated doses of nitrates and β-blockers.
    Which of the following medications would decrease the likelihood of a cardiovascular event in this patient?
    A. Angiotensin-converting enzyme inhibitors
    B. Angiotensin receptor blockers
    C. Digoxin
    D. Dihydropyridine calcium blockers
    E. Calcium channel blockers

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    why even bother with the obvious. Just know where you are need it and where you can help the most.

  2. #2
    hunteradam07 is offline Permanently Banned 511 points
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    If Cardiovascular events meaning MI, I think the answer is A/B, and I go with B cuz of less side effects: Dry cough! My logic is to decrease remodeling of heart, which is decrease demand of O2 on the heart tissue=Decrease MI risk. So I say B.

  3. #3
    paopaolong is offline Newbie
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    I go E.
    What is the answer?
    -Potter

    Hurry up, Potter. you have millon of things to do.

  4. #4
    thomasg2 is offline Newbie 510 points
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    Go for A

    ACEI inhibit remodelling of heart, vasodilating due to inhibition of the vasoconstricter Ang-II plus increase levers of Bradykinin which also is a potent vasod., inhibit aldosterone release, and decrease mortality over time. Do not have much effect on Hr and CO.

    ARB are given to p with negative side effects to ACEI like angioedema due to increased bradykinin levels.

  5. #5
    memphis is offline Newbie 510 points
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    I go with A. Ca blocker may not be right, since the heart rate is pretty low already

    I go with A. Ca blocker may not be right, since the heart rate is pretty low already

  6. #6
    OasisMan's Avatar
    OasisMan is offline Member 511 points
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    arent CCBs the drug of choice for exertional angina?
    "I have observed that the world has suffered far less from ignorance than from pretensions to knowledge. It is not skeptics or explorers but fanatics and ideologues who menace decency and progress. No agnostic ever burned anyone at the stake or tortured a pagan, a heretic, or an unbeliever."

  7. #7
    statiastudent347 is offline Junior Member 510 points
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    ace inhinitors for sure , final answer , lolol
    only thing really proven to decrease mortality in cvs disease
    what u got?

  8. #8
    Gottlima is offline Newbie 511 points
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    I agree with ******. ACE Inhibitors are the treatment of choice. There's no reason to start with an ARB unless they've failed the ACE Inhibitor due to SE's. Also, ARBs are less well-proven in reducing adverse outcomes compared to ACE Inhibitors.

  9. #9
    loka1282 is offline Junior Member 510 points
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    I would go for A

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