apoptosis but not necrosis

[pathologyguy]

Which of the following features characterizes apoptosis but not necrosis?

A. Disaggregation of polyribosomes
B. Eosinophilia
C. Inflammation
D. Karyolysis
E. Peripheral aggregation of chromatin

[Asclepius1]

I remember had seen this question somewhere but can't recall now......i will get back to this question later!

[maixungphong]

I look up defiinition of aptosis. It is program cell death. Necrosis is cell death due to hypoxemia. avascular necrosis of the femoral head is dead of the head of the femoral lack of blood supply.

My guess is D. It is hard.

[Asclepius1]

Necrosis is due to lack of oxygen and nutrients to the cell, which leads to its death. On the other hand, apoptosis is referring to cell suicide. It is getting enough oxygen and nutrients but it has lived as long as it can live.
There is no inflammation associated with apoptosis.


Necrosis is a word that describes the morphological changes that occur to a cell after its death. These include the following: (1) cellular swelling (2) denaturation of cytoplasmic proteins (gives rise to eosinophilia) (3) breakdown of cell organelles (4) a sequence of nuclear changes which include (a) karyolysis (b) pyknosis (c) karyorrhexis. There is inflammation.
How do remember this? pyknosis is the first thing that happens and is characterized by nuclear shrinkage (the word "pyknosis" reminds me of my pinky finger, the smallest finger, and so that is how I remember that pyknosis referst to nuclear shrinkage). Karyolysis refers to nuclear swelling not breakup because that is the karyorrhexis part of it. T. Rex, the dinasour, is going to breakup the nuclear membrane. Simply these three words are associated with breakdown of the nucleus.

Now try to answer the question.

[Asclepius1]

answer is C (100% sure)

[Asclepius1]

Sorry, I mean B (100% sure) NOT C...typo....Answer is B- 8)

[quachtinh]

Originally Posted by Swish

Necrosis is due to lack of oxygen and nutrients to the cell, which leads to its death. On the other hand, apoptosis is referring to cell suicide. It is getting enough oxygen and nutrients but it has lived as long as it can live.
There is no inflammation associated with apoptosis.


Necrosis is a word that describes the morphological changes that occur to a cell after its death. These include the following: (1) cellular swelling (2) denaturation of cytoplasmic proteins (gives rise to eosinophilia) (3) breakdown of cell organelles (4) a sequence of nuclear changes which include (a) karyolysis (b) pyknosis (c) karyorrhexis. There is inflammation.
How do remember this? pyknosis is the first thing that happens and is characterized by nuclear shrinkage (the word "pyknosis" reminds me of my pinky finger, the smallest finger, and so that is how I remember that pyknosis referst to nuclear shrinkage). Karyolysis refers to nuclear swelling not breakup because that is the karyorrhexis part of it. T. Rex, the dinasour, is going to breakup the nuclear membrane. Simply these three words are associated with breakdown of the nucleus.

Now try to answer the question.

Thanks for the hint.

My answer is E. Peripheral aggregation of chromatin