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Originally Posted by pathologyguy
In which of the following sites is embryonal rhabdomyosarcoma most likely to occur?
A. Gastrointestinal tract
B. Head and neck
C. Kidneys
D. Liver
E. Lungs
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The correct answer is B. Embryonal rhabdomyosarcoma is the most common form of rhabdomyosarcoma and is composed of cells resembling those found in developing muscle, predominately small, round cells. In embryonal rhabdomyosarcomas that protrude into an open space, the malignant cells immediately below the surface may be more densely packed, forming a "cambium" layer. The head and neck (particularly the nose, nasopharynx, and orbit) is the most frequent site for embryonal rhabdomyosarcoma; other favored sites are the genitourinary tract and the extremities.