ITP vs TTP

[BiscayneBlvd]

i know this is a very basic concept: ITP and TTP...but for some reason i'm having a hard time differentiating between the 2 of them. Does anybody have anything helpful to help me...


Thanks

[md90]

i know this is a very basic concept: ITP and TTP...but for some reason i'm having a hard time differentiating between the 2 of them. Does anybody have anything helpful to help me...

think vWF deficiency--one has it and the other does not--TTP does along with fever, renal failure, schistocytes, and CNS deficits...

Is all that I can think of.. ITP (I=Idiopathic) which is unknown cause, and believe that it occurs more in children and type II hypersensitivity..

[wcb22]

just remember, with TTP you will see schistocytes, and it is generally more serious than ITP. TTP is, for all intents and purposes, HUS (hemolytic uremic syndrome) in kids.

No schistocytes in ITP. It is associated with lupus, think autoimmune thrombocytopenia purpura. there are antibodies directed against the platelets.

[WarEagleMD]

I learned from my resident on internal medicine to remember "FAT RN" for diagnosing TTP:
F- fever
A- hemolytic anemia (schistocytes on smear)
T- thrombocytopenia
R- renal failure
N- neuro dysfunction (confusion, stupor, altered mental status)

[shilpakary]

nice info