#2 Early Signs Of Ischemia

[IMG SURVIVOR]

Why the cell well swell during early stage ischemia?
What medication works by inhibiting this pump?













Because the na, K pump will not work properly and the Na INSIDE will retain water.


digoxin

[md90]

will also have decreased ATP because ATP is part of the pump, causing the metabolic pathway to go in the direction of lactate (lactate acidosis) and NAD+/NADH, producing only two ATP;

Also with the Na/K pump not working, it gives Calcium easy access into the cell, activating various enzymes such as the proteases, endonucleases, and cytochrome c (mitochondria); leading to the destruction of the membranes of not only within the cell but the cell membrane...

[IMG SURVIVOR]

and the mitochondria will be swell and you will notice it by a dilatation of the inner mitochondria