I have been accepted and most likely will attend. I don't go there currently, so I can't help you out directly, but I've been debating different options and have some information that I got from a current 5th year student there that I can pass on. What follows are his words, slightly modified because he was answering some comparative questions, in an email to me:
The teaching is excellent. Charles University has an outstanding world wide reputation and it has brand new and fantastic facilities. You will have the pleasure of brand new state of the art equipment. They have built a whole new building for the pre-clinical years and it's pretty cool. Also construction for brand new Pediatrics building is underway some of which is already open.
The first year is one of the hardest. You have tests every week, lectures every day but there are plenty of libraries on Prague, one 24h library so finding a place to study wont be hard. Even with all this work you will still find MANY opportunities to party. So many restaurants, bars, cafes, clubs etc. you name it Prague has it. Many students go away some weekends to see Czech republic and there are some amazing things to see.
Everything you want and need is here in Prague and will give you the experience of a lifetime which you will never get a chance to have again. There is no other city I would choose to study in and at the end of the day I wouldn't do a single thing differently.
I don't know too much about housing. I plan on living in the student dormitories for a few months til I'm familiar enough with the town and settled in, then find a flat. It seems like the best option.
Hopefully this was a bit helpful