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Acetoacetyl-CoA in the b-oxidation of fatty acids
Acetoacetyl-CoA is involved in the b-oxidation of fatty acids I don't understand where it comes. Could anybody help??? |
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Look at the last round
In each round a two carbon fragment is released as acetyl CoA.
In the process of betaoxidation a beta-ketoacyl is formed in each round before the compound is broken into acetyl CoA and an acyl CoA with 2 carbon less than the original. So, in Beta oxidation of palmityl CoA you have 16 C, after the 1st round you have 14 C and so... In the last round you have a Beta-ketoacyl of only 4 carbons. This beta-ketoacyl is acetoacetyl CoA, before being broken into two acetyl CoA. |
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try this
http://www.rpi.edu/dept/bcbp/molbioc...1/fatcatab.htm or http://www.indstate.edu/thcme/mwking...oxidation.html Good Luck.
__________________
God Bless You. H. MD
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