Axon
07-08-2005, 02:38 PM
1486
If I give you five different answer choices of different organs and a picture of a biochem pathway, which choice is where BRANCHED CHAIN AMINO ACIDS broken down leucine, isoleucine, and valine? (Relate to Maple syrup urine disease).
a) Only muscle....
1487
You are treating and AIDS pt. with Didanosine. What side effects do Boards want you to KNOW?
a) when used alone or in combination with other medications, DIDANOSINE can cause serious damage to the liver and pancreas and a condition called lactic acidosis.
1488
If given a picture of TEN, or Toxic Epidermal Necrolysis, KNOW all the drugs that can cause its precipitation! Nearly all cases of TEN are induced by medications, and the mortality rate can approach 40%.
a) For medications used on a short-term basis, the relative risk was greatest for trimethoprim-sulfamethoxazole and other sulfonamide antibiotics, chlormezanone, aminopenicillins, quinolones, and cephalosporins.
1489
Pretend you are a USMLE Step 1 student shown picture of the world map...and...asked where is Vitamin C most deficient? (Parts of world labeled with abcde)
a) We dunno on this on, but likely in the poorer parts of the world are shown to lack this.
1490
Pt in poor country is bleeding on his nose a lot, but eats Vit C supplements. Which Vitamin is his most likely lacking? And what other symptoms can he have?
a) Vit K def. Recall that only colonic bacteria make this so babies are given Vit K shots. Know that in the adult, low dietary intake of Vit K is due to chronic illness, malnutrition, alcoholism, multiple abdominal surgeries, long-term parenteral nutrition, malabsorption, cholestatic disease, parenchymal liver disease, cystic fibrosis, inflammatory bowel disease, and drugs. Any one of those is asked a lot.
1491
Ulcerative colitis and Crohn's Dx. pts. ALWAYS need fat soluble vit supplements
1492
There was an old Disney story/question about a doctor who, before surgery, gave Snow White a drug to lower blood pressure. The classic drug starts with a (p) and affects alpha receptors. What is it?
A) phentolamine, a non selective alpha blocker.
1493
indinivir...what is it and where does it work in the cell?
a) This is a classic PROTEASE INHIBITOR. It stops protein assembly and processing in the late stages of HIV cell infection.
1494
Pt. presents w/ GI manifestations, including vomiting, abdominal pain, and melena for week. And generalized vasculitis involving the small vessels of the skin, along with some pain in the joints. (Hint: he had a cold 2 weeks ago).
What dx? What is the ANTIBODY usu. is associated?
a) Henoch-Schönlein purpura. IgA from mucosal membranes forms antibody-antigen complexes that deposit all over.
1495
This bug (hint: partially acid fast) is seen typically following oral surgery or in patients with poor dental hygiene. This form is characterized in the initial stages by soft-tissue swelling of the perimandibular area. Direct spread into the adjacent tissues occurs over time, along with development of fistulas that discharge purulent material containing yellow (ie, sulfur) granules. Picture of filamentous buggies shown on circular plate (looked like lines parallel to each other). What is this? Is it aerobic?
A) This is actinomycosis. This is ANAEROBIC.
If I give you five different answer choices of different organs and a picture of a biochem pathway, which choice is where BRANCHED CHAIN AMINO ACIDS broken down leucine, isoleucine, and valine? (Relate to Maple syrup urine disease).
a) Only muscle....
1487
You are treating and AIDS pt. with Didanosine. What side effects do Boards want you to KNOW?
a) when used alone or in combination with other medications, DIDANOSINE can cause serious damage to the liver and pancreas and a condition called lactic acidosis.
1488
If given a picture of TEN, or Toxic Epidermal Necrolysis, KNOW all the drugs that can cause its precipitation! Nearly all cases of TEN are induced by medications, and the mortality rate can approach 40%.
a) For medications used on a short-term basis, the relative risk was greatest for trimethoprim-sulfamethoxazole and other sulfonamide antibiotics, chlormezanone, aminopenicillins, quinolones, and cephalosporins.
1489
Pretend you are a USMLE Step 1 student shown picture of the world map...and...asked where is Vitamin C most deficient? (Parts of world labeled with abcde)
a) We dunno on this on, but likely in the poorer parts of the world are shown to lack this.
1490
Pt in poor country is bleeding on his nose a lot, but eats Vit C supplements. Which Vitamin is his most likely lacking? And what other symptoms can he have?
a) Vit K def. Recall that only colonic bacteria make this so babies are given Vit K shots. Know that in the adult, low dietary intake of Vit K is due to chronic illness, malnutrition, alcoholism, multiple abdominal surgeries, long-term parenteral nutrition, malabsorption, cholestatic disease, parenchymal liver disease, cystic fibrosis, inflammatory bowel disease, and drugs. Any one of those is asked a lot.
1491
Ulcerative colitis and Crohn's Dx. pts. ALWAYS need fat soluble vit supplements
1492
There was an old Disney story/question about a doctor who, before surgery, gave Snow White a drug to lower blood pressure. The classic drug starts with a (p) and affects alpha receptors. What is it?
A) phentolamine, a non selective alpha blocker.
1493
indinivir...what is it and where does it work in the cell?
a) This is a classic PROTEASE INHIBITOR. It stops protein assembly and processing in the late stages of HIV cell infection.
1494
Pt. presents w/ GI manifestations, including vomiting, abdominal pain, and melena for week. And generalized vasculitis involving the small vessels of the skin, along with some pain in the joints. (Hint: he had a cold 2 weeks ago).
What dx? What is the ANTIBODY usu. is associated?
a) Henoch-Schönlein purpura. IgA from mucosal membranes forms antibody-antigen complexes that deposit all over.
1495
This bug (hint: partially acid fast) is seen typically following oral surgery or in patients with poor dental hygiene. This form is characterized in the initial stages by soft-tissue swelling of the perimandibular area. Direct spread into the adjacent tissues occurs over time, along with development of fistulas that discharge purulent material containing yellow (ie, sulfur) granules. Picture of filamentous buggies shown on circular plate (looked like lines parallel to each other). What is this? Is it aerobic?
A) This is actinomycosis. This is ANAEROBIC.