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mjl1717
06-01-2003, 02:45 PM
What is the biochemical and or physiological mechanism of pain?
Anonymous
06-01-2003, 10:14 PM
What is the biochemical and or physiological mechanism of pain?

Cells of the immune system released cytokines to cause pain. http://www.pslgroup.com/dg/5b3d2.htm

In the periphery we have fast pricking pain transmitted by myelinated A-delta fibres, and 'slow' burning pain mediated by the primitive C fibres. In the spinal cord, the affective component of pain is transferred by spinoreticular fibres, and fibres to the medial thalamus, and thence to those parts of the cortex where 'sore' pain is perceived. The phylogenetically newer 'neospinothalamic tract' transmits discriminative components of pain to the SI cortex via the lateral thalamus.

http://www.westmeadanaesthesia.org/meetings/pain-physiology/Pain%20Physiology.htm