Anonymous
06-25-2004, 10:07 PM
initial vaccines against haemophilius influenzae type B prepared with capsular polysaccharides were not very effective in children less than 2 yo. subsequent vaccines have been greatly improved by the conjugation of the capsular polysaccharides to one of several proteins. why does this conjugation improve immunogenicity?
1. cd4+ T lymphocytes are activated
2. cycotoxic T lymphocytes responses are increased
3. direct activation od B lymphocytes by the vaccine is increased
4. nonimmune clearance of the vaccine is decreased
5. phagocytosis of the vaccine in increased
1. cd4+ T lymphocytes are activated
2. cycotoxic T lymphocytes responses are increased
3. direct activation od B lymphocytes by the vaccine is increased
4. nonimmune clearance of the vaccine is decreased
5. phagocytosis of the vaccine in increased