ahdy2000
06-22-2004, 10:12 AM
I got these from another site. Was wondering if somebody could help me answer them. The first 2 I think I have the answers to, the rest I don't know.
1.Primary structural protein for mitotic spindle apparatrus is
a.actin
b.desmin
c. myosin
d. tubulin ------> D
e. vimentin
2. Which of the following selectively binds to the epsilon chains of the T cell receptor?
a. anti lymphocyte globulin --------> A
b antitumor necrosis factor alpha monoclonal antibody
c azathioprine
d steroids
e cyclophosphamide
3. 75 male, has adequately controlled AF at rest. In stress the HR increases. Which of following will help to control ventricular response in exercise or stress?
a. adenosine
b. lidocaine
c. nifedepine
d. propranol
e. quinidine
4. Which modification of an active peptide will slow its metabolism leading to decreased clearance & increased half life?
a. decreasing no. of AA in peptide
b. administering peptide with enteric coating
c. ensuring free amino group at N terminal
d. Ensuring free carboxuyl group at the C terminal
e. substituting D for L AA
5. Stressed myocyte has no calcium gradient across its plasma memb. What has happened?
a. abortive mitosis
b. adaptation
c. cell death ------> C
d. repolarisation
e. reversible cell injury
6. Methimazole ..mech of action?
a. blocks binding of thyroxine to receptor
b. decrease uptake of I2 by thy globulin
c. inhibition of thy peroxidation activity
d. prevents proteolysis of thyroglobulin
e. stimulation of production of TBG
7. Afebrile 8 yr girl with post strep GN . (pic of glomeruli with neutron infilteration). What is the cause for cellulr infilterate
a. bradykinin
b. C5a
c.histamine
d. N formylated peptides#
e Serotionin
8. 6 yr girl with microcytic anaemia, cerebral edema & ataxia. Which enzyme to test for diagnosis?
a. 5 aminolev dehydrogenase
b. G6PD
c. LDH
d.Pyruvate Kinase
9. 19mth ingested Fe tablets. Has hepatic lysosomal degradation. Mech. Of action ?
a. activation of glutathione peroxidase
b. inhibitionof glutathione s transferase activity
c. peroxidation of DNA
d. peroxidation of memb lipids.
10. Protein with 30 AA structural motif with 4 cysteine residues co ordinated to Zn atom. Which of the following is has similar structure?
a. nucleosom
b. ribonuclease
c. ribosome
d. splicesome
e. transcription factor
11. vasoconstriction not blocked by prazocin & bradycardia blocked by scopolamine. Which drug was given?
a. amphetamine
b. angitensin
c. norepinephrine
d. phenylephrine
12. whch of the foll begins with interstitial edema, inflame cells, type 2 epitelial cell hypertrophy & hyperplasia?
a. anthracosis
b. asthma
c. centriacinar emphysema
d. chr. Bronchitis
e. pulm fibrosis ------> E sounds right
13. child born without limbs. Mutation for fibroblast growth factor is found. Which of the foll processes was affected?
a. apoptosis
b. differentiation
c. epithelial mesenchymal conversion
d. proliferation
14. eukaryotic protiein exists as a non membrane associated, glycosylated disulphide linked dimmer. mature forms are generally found in which compartment?
a. cytoplasm
b. extracellular space
c. mitochon matrix
d. nuclear matrix
e. nuclear pore
15. 45 male under dialysis for CRF starts erythropoietin theraphy. He has a hist of IDDM, peripheral neuropathy, & well controlled HT. Exacerbation of which of the following occurs?
a. chr. Renal insufficiency
b. DM
c. HT
d. Osteitis fibrosa cystica
e. Peripheral neuropathy
16. 60 male. With confusion & inability to concentrate. Which of the following used to assess concentration?
a. calculating sum of 4 numbers
b. recalling 4 unrelated words after 5 min
c. repeating a digit sequence backwards
d. reproducing figures from memory
e. writing from dictation
17. 15 male with infectious mononucleiosis . Sore throat. EBV first replicates in ? ----> B-cells (I think)
18. 45 female feels her feet are hot. On examination feet are pink dry & hot. Where is the defect?
a. Autonomic afferent
b. Post ganglionic sympathetic
c. Pre ganglionic sympathetic
d. Somatic cutaneous afferent
19. During clostridial myonecrosis, Clostridium perfringens saves itself from neutrophil by which mechanism?
1.Primary structural protein for mitotic spindle apparatrus is
a.actin
b.desmin
c. myosin
d. tubulin ------> D
e. vimentin
2. Which of the following selectively binds to the epsilon chains of the T cell receptor?
a. anti lymphocyte globulin --------> A
b antitumor necrosis factor alpha monoclonal antibody
c azathioprine
d steroids
e cyclophosphamide
3. 75 male, has adequately controlled AF at rest. In stress the HR increases. Which of following will help to control ventricular response in exercise or stress?
a. adenosine
b. lidocaine
c. nifedepine
d. propranol
e. quinidine
4. Which modification of an active peptide will slow its metabolism leading to decreased clearance & increased half life?
a. decreasing no. of AA in peptide
b. administering peptide with enteric coating
c. ensuring free amino group at N terminal
d. Ensuring free carboxuyl group at the C terminal
e. substituting D for L AA
5. Stressed myocyte has no calcium gradient across its plasma memb. What has happened?
a. abortive mitosis
b. adaptation
c. cell death ------> C
d. repolarisation
e. reversible cell injury
6. Methimazole ..mech of action?
a. blocks binding of thyroxine to receptor
b. decrease uptake of I2 by thy globulin
c. inhibition of thy peroxidation activity
d. prevents proteolysis of thyroglobulin
e. stimulation of production of TBG
7. Afebrile 8 yr girl with post strep GN . (pic of glomeruli with neutron infilteration). What is the cause for cellulr infilterate
a. bradykinin
b. C5a
c.histamine
d. N formylated peptides#
e Serotionin
8. 6 yr girl with microcytic anaemia, cerebral edema & ataxia. Which enzyme to test for diagnosis?
a. 5 aminolev dehydrogenase
b. G6PD
c. LDH
d.Pyruvate Kinase
9. 19mth ingested Fe tablets. Has hepatic lysosomal degradation. Mech. Of action ?
a. activation of glutathione peroxidase
b. inhibitionof glutathione s transferase activity
c. peroxidation of DNA
d. peroxidation of memb lipids.
10. Protein with 30 AA structural motif with 4 cysteine residues co ordinated to Zn atom. Which of the following is has similar structure?
a. nucleosom
b. ribonuclease
c. ribosome
d. splicesome
e. transcription factor
11. vasoconstriction not blocked by prazocin & bradycardia blocked by scopolamine. Which drug was given?
a. amphetamine
b. angitensin
c. norepinephrine
d. phenylephrine
12. whch of the foll begins with interstitial edema, inflame cells, type 2 epitelial cell hypertrophy & hyperplasia?
a. anthracosis
b. asthma
c. centriacinar emphysema
d. chr. Bronchitis
e. pulm fibrosis ------> E sounds right
13. child born without limbs. Mutation for fibroblast growth factor is found. Which of the foll processes was affected?
a. apoptosis
b. differentiation
c. epithelial mesenchymal conversion
d. proliferation
14. eukaryotic protiein exists as a non membrane associated, glycosylated disulphide linked dimmer. mature forms are generally found in which compartment?
a. cytoplasm
b. extracellular space
c. mitochon matrix
d. nuclear matrix
e. nuclear pore
15. 45 male under dialysis for CRF starts erythropoietin theraphy. He has a hist of IDDM, peripheral neuropathy, & well controlled HT. Exacerbation of which of the following occurs?
a. chr. Renal insufficiency
b. DM
c. HT
d. Osteitis fibrosa cystica
e. Peripheral neuropathy
16. 60 male. With confusion & inability to concentrate. Which of the following used to assess concentration?
a. calculating sum of 4 numbers
b. recalling 4 unrelated words after 5 min
c. repeating a digit sequence backwards
d. reproducing figures from memory
e. writing from dictation
17. 15 male with infectious mononucleiosis . Sore throat. EBV first replicates in ? ----> B-cells (I think)
18. 45 female feels her feet are hot. On examination feet are pink dry & hot. Where is the defect?
a. Autonomic afferent
b. Post ganglionic sympathetic
c. Pre ganglionic sympathetic
d. Somatic cutaneous afferent
19. During clostridial myonecrosis, Clostridium perfringens saves itself from neutrophil by which mechanism?