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IMG SURVIVOR
10-17-2008, 04:59 PM
A 14-year-old girl receives a bone marrow transplant as part of her treatment for acute lymphoblastic lymphoma. During the period of profound
immunosuppression before the marrow engrafts, she develops nonproductive cough, fever, mild hemoptysis, and pleuritic chest pain. A plain
chest x-ray film shows a pleuraI-based wedge-shaped lesion with focal cavitation. Open chest lung biopsy reveals necrosis and hemorrhage.
Septate fungal forms with dichotomous 45-degree branching are seen in the necrotic areas and involving the walls of several blood vessels.
When the fungus is cultured, it is found to be a monomorphic fungus.




Who is a monomorphic filamentous fungus?

PBateman
04-29-2009, 01:17 AM
Sounds like Aspergillus.

eldano
10-23-2009, 02:49 PM
That's definetly Aspergillous you got all the clues

1- immunesuppresion- commonly neutropenia
2-Hemoptysis
3- Septate fungal forms with dichotomous 45-degree branching are seen in the necrotic areas and involving the walls of several blood vessels. So you can differentiate from Rhizopus, Candida or Histoplasm
4- Also Aspergiollous likes Blood Vessels so you will commonly see areas of necrosis in near blood vessels