Question

[Baadshah]

A 65 - year - old male was brought to the ER with severe chest pain, sweating and nausea. EKG showed ST elevation in leads II, III and aVF. Medical management of acute myocardial infarction was initated. After initial treatment the pain decreased in intensity, but a reperfusion complex ventricular arrhythmia emerged. The arrhythmia was symptomatic and resolved spontaneously. Which of the following drugs was most likely responsible for rapid reperfusion in this patient?

A. Heparin
B. Argatroban
C. Warfarin
D. tPA
E. Aspirin
F. Ticlopidine
G. Abciximab
H. Cilostazol

[Closter]

tPA?
O.o
weird

[Baadshah]

That's what I figured. Just want to double check.

[hopelessMD]

I am surprised it doesn't ask for time period to administer drug and want method.

[mmod]

...............

[medic300107]

inferior wall MI...no good

[jabee_usm]

ummmmmmmmmmm

[Baadshah]

The stem asks which drug reperfuses a recently blocked coronary artery via an embolism. Seeing how this is an emergent situation, I would inject a drug via IV that is rapidly-acting and relatively fibrin-specific thrombolytic agent.

The only that come fits the bill is tPA or if asked more specifically alteplase.

[brob311]

tpa is the correct answer.

"Reperfusion may follow thrombolytic therapy (e.g. tpa)"

quoted from Goljan's rapid path review