atenolol

[IMG SURVIVOR]

We all know that for an overdose of atenolol we use glucago, but my question is:

What is MOA (mechanism of action) of glucagon in reversing the effects of atenolol?

[crazymed]

We all know that for an overdose of atenolol we use glucago, but my question is:

What is MOA (mechanism of action) of glucagon in reversing the effects of atenolol?


glucagon has positive ionotropic and chronotropic effect via glucagon receptor thatare Gprotein linked and inc adenly clyclase.

[MDiva]

glucagon has positive ionotropic and chronotropic effect via glucagon receptor thatare Gprotein linked and inc adenly clyclase.

To add, atenolol is a beta blocker. Beta receptors that it blocks normally stimulate adenyl cyclase via G protein, increase in cAMP. So OD of a beta blocker needs an antidote that will activate G protein's receptors. Glucagon does this.